Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:22836
Official Symbol:RHOBTB3
Other Aliases:KIAA0878
See related:HGNC:18757|MIM:607353|HPRD:09557
Chromosome:5
Location:5q15
Gene Description:Rho-related BTB domain containing 3
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0325
ORGANISM:human
Entrez Gene ID:22836
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Upregulated
Fold Change:1.23
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
73296CBCerebellum21.551610946655339.2724437713623
73296CTXCerebral cortex11.2966654300697.79210150241852
73296HIPHippocampal region13.375102043151912.4639039039612
73296HPFHippocampal formation10.69517052173619.2819230556488
73296HYHypothalamus7.285921186208725.36076277494431
73296LSXLateral septal complex4.393768787384034.29124855995178
73296MBMidbrain10.24680471420298.24322164058685
73296MYMedulla13.497293233871512.8446805477142
73296OLFOlfactory bulb37.17161893844632.5905160903931
73296PPons10.941347122192410.1630256175995
73296PALPallidum11.02759432792669.07187807559967
73296RHPRetrohippocampal region5.789721816778184.42582818865776
73296sAMYStriatum-like amygdalar nuclei5.83809736371044.215391933918
73296STRStriatum8.458409070968637.53382956981659
73296STRdStriatum dorsal region7.490917801856996.89373898506165
73296STRvStriatum ventral region14.843328475952111.9794142246246
73296THThalamus29.545041084289623.4208498001099
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
22836GO:0000004NDProcessbiological process unknown
22836GO:0003924NASFunctionGTPase activity
22836GO:0005515IEAFunctionprotein binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
22836RHBT3_HUMANO94955IPR000210BTBBTB
22836RHBT3_HUMANO94955IPR013069BTB_POZBTB/POZ

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