Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:23139
Official Symbol:MAST2
Other Aliases:FLJ39200|KIAA0807|MAST205|MTSSK|RP4-533D7.1
See related:HGNC:19035|HPRD:11294
Chromosome:1
Location:1p34.1
Gene Description:microtubule associated serine/threonine kinase 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0215
ORGANISM:human
Entrez Gene ID:23139
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:17776
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
17776CBCerebellum84.3881149291992100.0
17776CTXCerebral cortex100.0100.0
17776HIPHippocampal region85.2546615600586100.0
17776HPFHippocampal formation100.0100.0
17776HYHypothalamus100.0100.0
17776LSXLateral septal complex88.972839355468869.3669586181641
17776MBMidbrain100.0100.0
17776MYMedulla95.1109924316406100.0
17776OLFOlfactory bulb100.0100.0
17776PPons88.8016586303711100.0
17776PALPallidum95.0589904785156100.0
17776RHPRetrohippocampal region100.0100.0
17776sAMYStriatum-like amygdalar nuclei100.091.8697814941406
17776STRStriatum59.044219970703148.8380470275879
17776STRdStriatum dorsal region46.647727966308640.237003326416
17776STRvStriatum ventral region68.125663757324250.1014671325684
17776THThalamus89.408958435058682.4013442993164
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
23139GO:0000166IEAFunctionnucleotide binding
23139GO:0000287ISSFunctionmagnesium ion binding
23139GO:0004674IEAFunctionprotein serine/threonine kinase activity
23139GO:0005515IPIFunctionprotein binding
23139GO:0005524ISSFunctionATP binding
23139GO:0005856IEAComponentcytoskeleton
23139GO:0006468ISSProcessprotein amino acid phosphorylation
23139GO:0016020IEAComponentmembrane
23139GO:0016740IEAFunctiontransferase activity
23139GO:0019902IPIFunctionphosphatase binding
23139GO:0045075ISSProcessregulation of interleukin-12 biosynthesis
23139GO:0048515ISSProcessspermatid differentiation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
AAH65499.1--TubulinHPRD11294
AAH65499.1--Protocadherin LKCHPRD11294
AAH65499.127148NP_056505.1serine/threonine kinase 36 (fused homolog, Drosophila)HPRD11294
AAH65499.154825NP_060145.2protocadherin LKC precursorHPRD15103
AAH65499.154825NP_060145.2protocadherin LKC precursorHPRD11294
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
23139IPR013543CaMKII_ADCalcium/calmodulin dependent protein kinase II, association-domain
23139IPR001478PDZPDZ/DHR/GLGF
23139IPR000961Pkinase_CProtein kinase, C-terminal
23139IPR000719Prot_kinaseProtein kinase
23139IPR008271Ser_thr_pkin_ASSerine/threonine protein kinase, active site
23139IPR001245Tyr_pkinaseTyrosine protein kinase
23139IPR013695WAKWall-associated kinase

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