Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:23175
Official Symbol:LPIN1
Other Aliases:DKFZp781P1796|KIAA0188
See related:HGNC:13345|MIM:605518|HPRD:09271
Chromosome:2
Location:2p25.1
Gene Description:lipin 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0318
ORGANISM:human
Entrez Gene ID:23175
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Upregulated
Fold Change:0.64
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14245CBCerebellum25.331991195678741.4997119903564
14245CTXCerebral cortex53.598250389099141.9995441436768
14245HIPHippocampal region29.039108276367234.5544481277466
14245HPFHippocampal formation31.656601905822831.6480736732483
14245HYHypothalamus55.238079071044948.4988231658936
14245LSXLateral septal complex25.024479389190717.9152264595032
14245MBMidbrain52.010690689086956.839316368103
14245MYMedulla63.477161407470782.3283157348633
14245OLFOlfactory bulb54.003413200378444.910327911377
14245PPons58.265611648559674.4959926605225
14245PALPallidum57.615747451782262.0805358886719
14245RHPRetrohippocampal region36.482472896575928.8531918525696
14245sAMYStriatum-like amygdalar nuclei62.842704772949250.4031095504761
14245STRStriatum36.190557956695627.9240078926086
14245STRdStriatum dorsal region31.289294242858924.2248430252075
14245STRvStriatum ventral region42.75499725341831.6232314109802
14245THThalamus40.093012332916336.4040775299072
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
23175GO:0005554NDFunctionmolecular function unknown
23175GO:0005634ISSComponentnucleus
23175GO:0045444ISSProcessfat cell differentiation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
23175LPIN1_HUMANQ14693IPR007651Lipin_NLipin, N-terminal conserved region
23175LPIN1_HUMANQ14693IPR013209LNS2LNS2, Lipin/Ned1/Smp2

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