Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:23198
Official Symbol:PSME4
Other Aliases:FLJ21864|KIAA0077|MGC138374|PA200
See related:HGNC:20635|MIM:607705|HPRD:09652
Chromosome:2
Location:2p16.2
Gene Description:proteasome (prosome, macropain) activator subunit 4
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0093
ORGANISM:human
Entrez Gene ID:23198
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15009677
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Upregulated
Fold Change:0.50 :: 0.03 :: 0.28 :: 0.42 :: 0.74 :: -0.13 :: 0.34 :: 0.05 :: 0.69 :: 0.61
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
103554CBCerebellum19.113895416259819.6302738189697
103554CTXCerebral cortex74.708564758300854.5802612304688
103554HIPHippocampal region38.73986053466848.2070274353027
103554HPFHippocampal formation39.967189788818440.9098968505859
103554HYHypothalamus12.90198707580578.98202133178711
103554LSXLateral septal complex49.523826599121131.6741943359375
103554MBMidbrain22.529731750488319.2273864746094
103554MYMedulla30.855165481567432.3898506164551
103554OLFOlfactory bulb71.051979064941463.048656463623
103554PPons30.115949630737330.0115585327148
103554PALPallidum18.981918334960914.7636108398438
103554RHPRetrohippocampal region42.392444610595731.9990425109863
103554sAMYStriatum-like amygdalar nuclei20.09850311279314.1280727386475
103554STRStriatum26.009157180786117.0873508453369
103554STRdStriatum dorsal region22.329435348510714.7817258834839
103554STRvStriatum ventral region30.717941284179719.2032985687256
103554THThalamus36.684730529785228.8443222045898
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
23198GO:0005488IEAFunctionbinding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
23198IPR000357HEATHEAT

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