Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:23209
Official Symbol:MLC1
Other Aliases:KIAA0027|LVM|MLC|VL
See related:HGNC:17082|MIM:605908|HPRD:05800
Chromosome:22
Location:22q13.33
Gene Description:megalencephalic leukoencephalopathy with subcortical cysts 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0898
ORGANISM:human
Entrez Gene ID:23209
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.6 :: -1.7 :: -2.4 :: -3.9
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
170790CBCerebellum50.011449813842870.6231269836426
170790CTXCerebral cortex72.084222793579153.2384471893311
170790HIPHippocampal region72.997690200805757.41015625
170790HPFHippocampal formation78.232849121093861.0305099487305
170790HYHypothalamus79.770587921142653.1984691619873
170790LSXLateral septal complex86.380741119384865.7686252593994
170790MBMidbrain38.758489608764627.7932424545288
170790MYMedulla58.062389373779346.0500297546387
170790OLFOlfactory bulb99.574531555175877.8983116149902
170790PPons47.486558914184636.2571811676025
170790PALPallidum36.838203430175824.7266778945923
170790RHPRetrohippocampal region87.061679840087962.9697761535645
170790sAMYStriatum-like amygdalar nuclei71.217391967773448.0250797271729
170790STRStriatum43.64676475524932.3123188018799
170790STRdStriatum dorsal region29.757594108581526.8219804763794
170790STRvStriatum ventral region54.583456039428727.9426689147949
170790THThalamus27.769311904907220.2683353424072
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
23209GO:0000004NDProcessbiological process unknown
23209GO:0000299TASComponentintegral to membrane of membrane fraction
23209GO:0003735IEAFunctionstructural constituent of ribosome
23209GO:0005216IEAFunctionion channel activity
23209GO:0005554NDFunctionmolecular function unknown
23209GO:0005622IEAComponentintracellular
23209GO:0005840IEAComponentribosome
23209GO:0006412IEAProcessprotein biosynthesis
23209GO:0006811IEAProcession transport
23209GO:0016020IEAComponentmembrane
23209GO:0016021IEAComponentintegral to membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
23209MLC1_HUMANQ15049IPR001209Ribosomal_S14Ribosomal protein S14

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