Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:23316
Official Symbol:CUTL2
Other Aliases:CUX2
See related:HGNC:19347|HPRD:10851
Chromosome:12
Location:12q24.11-q24.12
Gene Description:cut-like 2 (Drosophila)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0925
ORGANISM:human
Entrez Gene ID:23316
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.4 :: 1.4
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
13048CBCerebellum63.920436859130985.6145057678223
13048CTXCerebral cortex100.0100.0
13048HIPHippocampal region33.621264457702646.0201759338379
13048HPFHippocampal formation57.005599975585977.9917793273926
13048HYHypothalamus57.582149505615251.2243900299072
13048LSXLateral septal complex38.995912551879932.0310316085815
13048MBMidbrain73.930461883544973.7826156616211
13048MYMedulla72.804107666015687.7974243164062
13048OLFOlfactory bulb87.106555938720799.6044235229492
13048PPons68.144657135009876.0793952941895
13048PALPallidum52.762987136840854.7591190338135
13048RHPRetrohippocampal region90.9372329711914100.0
13048sAMYStriatum-like amygdalar nuclei70.032041549682664.6051502227783
13048STRStriatum48.284663200378446.040678024292
13048STRdStriatum dorsal region31.824694633483927.0417943000793
13048STRvStriatum ventral region85.692565917968888.2747192382812
13048THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
23316GO:0003700NASFunctiontranscription factor activity
23316GO:0005634NASComponentnucleus
23316GO:0006355NASProcessregulation of transcription, DNA-dependent
23316GO:0043565IEAFunctionsequence-specific DNA binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
23316CUTL2_HUMANO14529IPR007108Cut_homeoCut homeobox
23316CUTL2_HUMANO14529IPR003350Hmoeo_CUTHomeodomain protein CUT
23316CUTL2_HUMANO14529IPR001356HomeoboxHomeobox
23316CUTL2_HUMANO14529IPR000694PRO_richProline-rich region

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