Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:23413
Official Symbol:FREQ
Other Aliases:DKFZp761L1223|FLUP|NCS-1|NCS1
See related:HGNC:3953|MIM:603315|HPRD:04500
Chromosome:9
Location:9q34
Gene Description:frequenin homolog (Drosophila)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0419
ORGANISM:human
Entrez Gene ID:23413
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:65153
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14299CBCerebellum56.19244003295968.19091796875
14299CTXCerebral cortex100.0100.0
14299HIPHippocampal region69.2504806518555100.0
14299HPFHippocampal formation84.2148971557617100.0
14299HYHypothalamus76.89612579345782.9099960327148
14299LSXLateral septal complex84.484214782714869.3978576660156
14299MBMidbrain76.365280151367294.7813949584961
14299MYMedulla90.2179489135742100.0
14299OLFOlfactory bulb100.0100.0
14299PPons76.2101440429688100.0
14299PALPallidum78.418144226074296.1470718383789
14299RHPRetrohippocampal region100.0100.0
14299sAMYStriatum-like amygdalar nuclei100.0100.0
14299STRStriatum81.3295898437570.437744140625
14299STRdStriatum dorsal region72.380332946777363.3222579956055
14299STRvStriatum ventral region87.840835571289169.3365783691406
14299THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
23413GO:0005509TASFunctioncalcium ion binding
23413GO:0005795IEAComponentGolgi stack
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_055101.2--PI4K betaHPRD04500
NP_055101.2--Kv4.2HPRD04500
NP_055101.2--IL1RAPLHPRD04500
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
23413NCS1_HUMANP62166IPR013567EF_hand_assoc_2EF hand associated, type-2
23413NCS1_HUMANP62166IPR002048EF_hand_Ca_bdCalcium-binding EF-hand
23413NCS1_HUMANP62166IPR013684Miro-likeMiro-like
23413NCS1_HUMANP62166IPR013623NADPH_OxNADPH oxidase Respiratory burst
23413NCS1_HUMANP62166IPR001125RecoverinRecoverin

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