Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:23426
Official Symbol:GRIP1
Other Aliases:GRIP
See related:HGNC:18708|MIM:604597
Chromosome:12
Location:12q14.3
Gene Description:glutamate receptor interacting protein 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0512
ORGANISM:human
Entrez Gene ID:23426
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:84016
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
74053CBCerebellum19.837627410888721.4819850921631
74053CTXCerebral cortex35.900735855102521.8014645576477
74053HIPHippocampal region35.028445243835434.2563886642456
74053HPFHippocampal formation40.034824371337932.1506299972534
74053HYHypothalamus11.17048287391667.55082505941391
74053LSXLateral septal complex45.268492698669427.9512429237366
74053MBMidbrain14.775128841400111.2628512382507
74053MYMedulla13.38251113891611.3632445335388
74053OLFOlfactory bulb48.656433105468836.4749145507812
74053PPons13.354866504669210.1039085388184
74053PALPallidum20.128353595733614.3589329719543
74053RHPRetrohippocampal region48.225116729736330.1253333091736
74053sAMYStriatum-like amygdalar nuclei23.545944213867213.4260983467102
74053STRStriatum22.387955188751215.6154773235321
74053STRdStriatum dorsal region19.747361183166515.2138595581055
74053STRvStriatum ventral region20.785407543182412.699417591095
74053THThalamus17.485282897949213.8330442905426
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
23426GO:0003713NASFunctiontranscription coactivator activity
23426GO:0005515NASFunctionprotein binding
23426GO:0005783IEAComponentendoplasmic reticulum
23426GO:0007242NASProcessintracellular signaling cascade
23426GO:0008372NDComponentcellular component unknown
23426GO:0030159NASFunctionreceptor signaling complex scaffold activity
23426GO:0030521NASProcessandrogen receptor signaling pathway
23426GO:0045211IEAComponentpostsynaptic membrane
23426GO:0045893NASProcesspositive regulation of transcription, DNA-dependent
23426GO:0050681NASFunctionandrogen receptor binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
XP_290559.5---BIND183931
XP_290559.526136NP_056456.1testin isoform 1BIND134127
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
23426IPR001478PDZPDZ/DHR/GLGF
23426GRIP1_HUMANQ9Y3R0IPR001478PDZPDZ/DHR/GLGF

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