Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:23451
Official Symbol:SF3B1
Other Aliases:PRP10|PRPF10|SAP155|SF3b155
See related:HGNC:10768|MIM:605590|HPRD:09281
Chromosome:2
Location:2q33.1
Gene Description:splicing factor 3b, subunit 1, 155kDa
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0247
ORGANISM:human
Entrez Gene ID:23451
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:81898
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
81898CBCerebellum7.424526214599616.72441291809082
81898CTXCerebral cortex24.483821868896516.8788509368896
81898HIPHippocampal region27.848798751831129.1449356079102
81898HPFHippocampal formation25.073862075805723.0385437011719
81898HYHypothalamus2.161304473876951.54475486278534
81898LSXLateral septal complex11.68296146392827.81715488433838
81898MBMidbrain3.793604612350462.98123788833618
81898MYMedulla8.423488616943368.39231872558594
81898OLFOlfactory bulb24.441612243652317.0731143951416
81898PPons4.128634452819824.10575723648071
81898PALPallidum3.804411649703982.86500310897827
81898RHPRetrohippocampal region20.097276687622114.3344736099243
81898sAMYStriatum-like amygdalar nuclei6.328577518463134.17084550857544
81898STRStriatum14.741435050964410.1186809539795
81898STRdStriatum dorsal region14.855216026306210.2810506820679
81898STRvStriatum ventral region21.293920516967814.0804510116577
81898THThalamus6.457503795623784.88884449005127
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
23451GO:0000398NASProcessnuclear mRNA splicing, via spliceosome
23451GO:0005488IEAFunctionbinding
23451GO:0005681NASComponentspliceosome complex
23451GO:0031202NASFunctionRNA splicing factor activity, transesterification mechanism
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_036565.1--SF3BHPRD09281
NP_036565.151639NP_057131.1splicing factor 3B, 14 kDa subunitHPRD09702
NP_036565.151639NP_057131.1splicing factor 3B, 14 kDa subunitHPRD09281
NP_036565.184844NP_116147.1PHD-finger 5AHPRD15126
NP_036565.251639NP_057131.1splicing factor 3B, 14 kDa subunitBIND180494
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
23451SF3B1_HUMANO75533IPR008081FragX_IPCytoplasmic fragile X mental retardation protein interacting protein
23451SF3B1_HUMANO75533IPR000357HEATHEAT

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.