Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:23678
Official Symbol:SGK3
Other Aliases:CISK|DKFZp781N0293|SGK2|SGKL
See related:HGNC:10812|MIM:607591|HPRD:06349
Chromosome:8
Location:8q12.3-8q13.1
Gene Description:serum/glucocorticoid regulated kinase family, member 3
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0240
ORGANISM:human
Entrez Gene ID:23678
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:170755
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
170755CBCerebellum1.991890877485283.23352274298668
170755CTXCerebral cortex4.656326055526733.20726072788239
170755HIPHippocampal region0.4141437411308290.443951576948166
170755HPFHippocampal formation1.382492288947110.674817278981209
170755HYHypothalamus0.098816916346550.0942875444889069
170755LSXLateral septal complex0.5274752974510190.241838827729225
170755MBMidbrain0.6722763180732730.699451416730881
170755MYMedulla3.077791094779973.4219896197319
170755OLFOlfactory bulb2.606290161609651.31312775611877
170755PPons0.8817268311977390.95359542965889
170755PALPallidum1.457968235015870.658780828118324
170755RHPRetrohippocampal region2.571272477507590.910285666584969
170755sAMYStriatum-like amygdalar nuclei3.179670736193661.14786131680012
170755STRStriatum10.25576770305633.81811058521271
170755STRdStriatum dorsal region11.36634361743934.16487300395966
170755STRvStriatum ventral region12.9370417594914.68851757049561
170755THThalamus1.989471942186362.59969809651375
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
23678GO:0000166IEAFunctionnucleotide binding
23678GO:0004674IEAFunctionprotein serine/threonine kinase activity
23678GO:0004674TASFunctionprotein serine/threonine kinase activity
23678GO:0004713IEAFunctionprotein-tyrosine kinase activity
23678GO:0005515IEAFunctionprotein binding
23678GO:0005524IEAFunctionATP binding
23678GO:0006468IEAProcessprotein amino acid phosphorylation
23678GO:0006468TASProcessprotein amino acid phosphorylation
23678GO:0006950TASProcessresponse to stress
23678GO:0007242IEAProcessintracellular signaling cascade
23678GO:0016740IEAFunctiontransferase activity
23678GO:0035091IEAFunctionphosphoinositide binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
23678IPR013543CaMKII_ADCalcium/calmodulin dependent protein kinase II, association-domain
23678IPR000961Pkinase_CProtein kinase, C-terminal
23678IPR000719Prot_kinaseProtein kinase
23678IPR001683PXPhox-like
23678IPR008271Ser_thr_pkin_ASSerine/threonine protein kinase, active site
23678IPR001245Tyr_pkinaseTyrosine protein kinase
23678IPR013695WAKWall-associated kinase
23678SGK3_HUMANQ96BR1IPR013543CaMKII_ADCalcium/calmodulin dependent protein kinase II, association-domain
23678SGK3_HUMANQ96BR1IPR000961Pkinase_CProtein kinase, C-terminal
23678SGK3_HUMANQ96BR1IPR000719Prot_kinaseProtein kinase
23678SGK3_HUMANQ96BR1IPR001683PXPhox-like
23678SGK3_HUMANQ96BR1IPR008271Ser_thr_pkin_ASSerine/threonine protein kinase, active site
23678SGK3_HUMANQ96BR1IPR001245Tyr_pkinaseTyrosine protein kinase
23678SGK3_HUMANQ96BR1IPR013695WAKWall-associated kinase

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