Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2565
Official Symbol:GABRG1
Other Aliases:DKFZp686H2042|MGC33838
See related:HGNC:4086|MIM:137166|HPRD:15923
Chromosome:4
Location:4p12
Gene Description:gamma-aminobutyric acid (GABA) A receptor, gamma 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0606
ORGANISM:human
Entrez Gene ID:2565
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:140674
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:HOT0290
ORGANISM:human
Entrez Gene ID:2565
Evidence Type:Whole Genome Association
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14405CBCerebellum4.458776831626896.35819363594055
14405CTXCerebral cortex2.675389021635062.57322710752487
14405HIPHippocampal region1.855797380208972.07010042667389
14405HPFHippocampal formation2.071889728307721.96702580153942
14405HYHypothalamus16.33622527122513.5428229570389
14405LSXLateral septal complex32.380161285400422.2948384284973
14405MBMidbrain5.850299119949344.8232586979866
14405MYMedulla11.353132963180512.4804663658142
14405OLFOlfactory bulb10.1249411106118.17951130867004
14405PPons5.74327015876775.58219587802887
14405PALPallidum31.961152076721228.836528301239
14405RHPRetrohippocampal region2.437400043010711.86490899324417
14405sAMYStriatum-like amygdalar nuclei32.791999816894523.3195486068726
14405STRStriatum8.572427749633796.17929077148438
14405STRdStriatum dorsal region1.802891597151761.49621398001909
14405STRvStriatum ventral region7.797288775444035.55447238683701
14405THThalamus3.393595576286322.94367222487926
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2565GO:0004890IEAFunctionGABA-A receptor activity
2565GO:0005216IEAFunctionion channel activity
2565GO:0005230IEAFunctionextracellular ligand-gated ion channel activity
2565GO:0006811IEAProcession transport
2565GO:0006821IEAProcesschloride transport
2565GO:0007214IEAProcessgamma-aminobutyric acid signaling pathway
2565GO:0016021IEAComponentintegral to membrane
2565GO:0030594IEAFunctionneurotransmitter receptor activity
2565GO:0045211IEAComponentpostsynaptic membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2565GBRG1_HUMANQ8N1C3IPR001390GABAAa_rcptGamma-aminobutyric-acid A receptor, alpha subunit
2565GBRG1_HUMANQ8N1C3IPR006028GABAA_rcptGamma-aminobutyric acid A receptor
2565GBRG1_HUMANQ8N1C3IPR005438GABBAg1_rcptGamma-aminobutyric-acid A receptor, gamma 1 subunit
2565GBRG1_HUMANQ8N1C3IPR005437GABBAg_rcptGamma-aminobutyric-acid A receptor, gamma subunit
2565GBRG1_HUMANQ8N1C3IPR006201Neur_channelNeurotransmitter-gated ion-channel
2565GBRG1_HUMANQ8N1C3IPR006202Neur_chan_lig_bdNeurotransmitter-gated ion-channel ligand-binding
2565GBRG1_HUMANQ8N1C3IPR006029Neu_channel_TMNeurotransmitter-gated ion-channel transmembrane region

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