Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2572
Official Symbol:GAD2
Other Aliases:GAD65
See related:HGNC:4093|MIM:138275|HPRD:11817
Chromosome:10
Location:10p11.23
Gene Description:glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0607
ORGANISM:human
Entrez Gene ID:2572
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24380
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14417CBCerebellum100.0100.0
14417CTXCerebral cortex100.0100.0
14417HIPHippocampal region100.0100.0
14417HPFHippocampal formation100.0100.0
14417HYHypothalamus100.0100.0
14417LSXLateral septal complex100.0100.0
14417MBMidbrain100.0100.0
14417MYMedulla100.0100.0
14417OLFOlfactory bulb100.0100.0
14417PPons100.0100.0
14417PALPallidum100.0100.0
14417RHPRetrohippocampal region100.0100.0
14417sAMYStriatum-like amygdalar nuclei100.0100.0
14417STRStriatum100.0100.0
14417STRdStriatum dorsal region100.0100.0
14417STRvStriatum ventral region100.0100.0
14417THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2572GO:0004351IEAFunctionglutamate decarboxylase activity
2572GO:0005515IPIFunctionprotein binding
2572GO:0006540TASProcessglutamate decarboxylation to succinate
2572GO:0007268TASProcesssynaptic transmission
2572GO:0016829IEAFunctionlyase activity
2572GO:0016831IEAFunctioncarboxy-lyase activity
2572GO:0019752IEAProcesscarboxylic acid metabolism
2572GO:0042136IEAProcessneurotransmitter biosynthesis
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_000809.15581NP_005391.1protein kinase C, epsilonHPRD11817
NP_000809.123390NP_056151.1huntingtin interacting protein 14BIND195710
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2572DCE2_HUMANQ05329IPR013090Phospholip_A2_ASPhospholipase A2, active site
2572DCE2_HUMANQ05329IPR002129Pyridoxal_deCPyridoxal-dependent decarboxylase

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.