Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:26047
Official Symbol:CNTNAP2
Other Aliases:CASPR2|CDFE|DKFZp781D1846|NRXN4
See related:HGNC:13830|MIM:604569|HPRD:05197
Chromosome:7
Location:7q35-q36
Gene Description:contactin associated protein-like 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0333
ORGANISM:human
Entrez Gene ID:26047
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:-0.54
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
66797CBCerebellum53.830226898193476.060962677002
66797CTXCerebral cortex100.0100.0
66797HIPHippocampal region100.0100.0
66797HPFHippocampal formation100.0100.0
66797HYHypothalamus100.0100.0
66797LSXLateral septal complex100.0100.0
66797MBMidbrain100.0100.0
66797MYMedulla99.3313522338867100.0
66797OLFOlfactory bulb100.0100.0
66797PPons100.0100.0
66797PALPallidum100.0100.0
66797RHPRetrohippocampal region100.0100.0
66797sAMYStriatum-like amygdalar nuclei100.0100.0
66797STRStriatum100.0100.0
66797STRdStriatum dorsal region100.0100.0
66797STRvStriatum ventral region100.0100.0
66797THThalamus100.099.2257766723633
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
26047GO:0005515IEAFunctionprotein binding
26047GO:0007155IEAProcesscell adhesion
26047GO:0008038NASProcessneuron recognition
26047GO:0016020IEAComponentmembrane
26047GO:0016021NASComponentintegral to membrane
26047GO:0019226NASProcesstransmission of nerve impulse
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_054860.157178NP_065071.1retinoic acid induced 17HPRD12115
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
26047CNTP2_HUMANQ9UHC6IPR000742EGF_3EGF-like, type 3
26047CNTP2_HUMANQ9UHC6IPR006209EGF_likeEGF-like
26047CNTP2_HUMANQ9UHC6IPR000421FA58_CCoagulation factor 5/8 type, C-terminal
26047CNTP2_HUMANQ9UHC6IPR001545Gly_hormoneBGonadotropin, beta chain
26047CNTP2_HUMANQ9UHC6IPR001791Laminin_GLaminin G
26047CNTP2_HUMANQ9UHC6IPR012679Laminin_G_1Laminin G, subdomain 1
26047CNTP2_HUMANQ9UHC6IPR012680Laminin_G_2Laminin G, subdomain 2
26047CNTP2_HUMANQ9UHC6IPR006025Pept_M_Zn_BSPeptidase M, neutral zinc metallopeptidases, zinc-binding site

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