Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2657
Official Symbol:GDF1
Other Aliases:-
See related:HGNC:4214|MIM:602880|HPRD:04194
Chromosome:19
Location:19p12
Gene Description:growth differentiation factor 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0888
ORGANISM:human
Entrez Gene ID:2657
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.4 :: -1.5 :: -1.7 :: -1.7
KARG Evidence 2
KARG ID:EVIM0907
ORGANISM:human
Entrez Gene ID:2657
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.4 :: -1.5 :: -1.7 :: -1.7
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14562CBCerebellum15.779171943664617.5202732086182
14562CTXCerebral cortex41.376159667968831.1272468566895
14562HIPHippocampal region35.542930603027349.389030456543
14562HPFHippocampal formation37.034778594970741.6065788269043
14562HYHypothalamus24.440557479858420.6945018768311
14562LSXLateral septal complex20.440015792846714.2642469406128
14562MBMidbrain24.997535705566423.4740238189697
14562MYMedulla30.053548812866232.0913467407227
14562OLFOlfactory bulb35.227985382080128.4415855407715
14562PPons25.637516021728526.8845233917236
14562PALPallidum12.468248367309610.6064672470093
14562RHPRetrohippocampal region41.194877624511732.9286079406738
14562sAMYStriatum-like amygdalar nuclei2.523915052413942.14419341087341
14562STRStriatum17.916894912719712.7814741134644
14562STRdStriatum dorsal region17.154272079467812.3192873001099
14562STRvStriatum ventral region25.121486663818417.1544799804688
14562THThalamus18.973564147949216.398832321167
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2657GO:0005125IEAFunctioncytokine activity
2657GO:0005615IEAComponentextracellular space
2657GO:0008083IEAFunctiongrowth factor activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2657GDF1_HUMANP27539IPR002405Inhibin_alphaInhibin, alpha subunit
2657GDF1_HUMANP27539IPR001839TGFbTransforming growth factor beta

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