Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2683
Official Symbol:B4GALT1
Other Aliases:B4GAL-T1|DKFZp686N19253|GGTB2|GT1|GTB|MGC50983|beta4Gal-T1
See related:HGNC:924|MIM:137060|HPRD:00659
Chromosome:9
Location:9p13
Gene Description:UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0322
ORGANISM:human
Entrez Gene ID:2683
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:-0.64
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14595CBCerebellum9.539411544799812.6107106208801
14595CTXCerebral cortex8.357331037521366.38687944412231
14595HIPHippocampal region5.457540988922125.09671425819397
14595HPFHippocampal formation9.704387187957769.11073923110962
14595HYHypothalamus3.340793132781982.94376230239868
14595LSXLateral septal complex0.7358247637748720.788509905338287
14595MBMidbrain11.065163612365715.186439037323
14595MYMedulla12.686455249786414.7812538146973
14595OLFOlfactory bulb6.686582326889045.31560683250427
14595PPons7.851988554000859.41032576560974
14595PALPallidum1.188253253698351.23776495456696
14595RHPRetrohippocampal region14.706504344940212.5650706291199
14595sAMYStriatum-like amygdalar nuclei1.437769889831542.35708484053612
14595STRStriatum2.636733710765842.42534077167511
14595STRdStriatum dorsal region2.821042239665992.51277577877045
14595STRvStriatum ventral region1.538539409637451.14484092593193
14595THThalamus29.906478881835927.6856136322021
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2683GO:0003831IEAFunctionbeta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
2683GO:0003945IEAFunctionN-acetyllactosamine synthase activity
2683GO:0005795IEAComponentGolgi stack
2683GO:0005975IEAProcesscarbohydrate metabolism
2683GO:0008378NASFunctiongalactosyltransferase activity
2683GO:0009312NASProcessoligosaccharide biosynthesis
2683GO:0016020IEAComponentmembrane
2683GO:0016021IEAComponentintegral to membrane
2683GO:0016757IEAFunctiontransferase activity, transferring glycosyl groups
2683GO:0030145IEAFunctionmanganese ion binding
2683GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001488.23906NP_002280.1lactalbumin, alpha- precursorHPRD00659
NP_001488.23906NP_002280.1lactalbumin, alpha- precursorHPRD01024
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2683B4GT1_HUMANP15291IPR003859Galactosyl_T_2Metazoa galactosyltransferase

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