Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:27039
Official Symbol:PKD2L2
Other Aliases:-
See related:HGNC:9012|MIM:604669|HPRD:05238
Chromosome:5
Location:5q31
Gene Description:polycystic kidney disease 2-like 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0169
ORGANISM:human
Entrez Gene ID:27039
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:53871
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
53871CBCerebellum2.365210294723514.43718671798706
53871CTXCerebral cortex0.3273156583309170.564180493354797
53871HIPHippocampal region0.3529805839061740.767381548881531
53871HPFHippocampal formation0.2627079486846920.491915374994278
53871HYHypothalamus0.100710622966290.0740921348333359
53871LSXLateral septal complex0.0954957678914070.199888899922371
53871MBMidbrain0.2348461151123050.437129616737366
53871MYMedulla0.2456841468811040.320954382419586
53871OLFOlfactory bulb0.3107958436012270.300736606121063
53871PPons0.1673972755670550.21240009367466
53871PALPallidum0.1405045241117480.346724212169647
53871RHPRetrohippocampal region0.1117758005857470.103568896651268
53871sAMYStriatum-like amygdalar nuclei0.2349672913551330.229613244533539
53871STRStriatum0.1613402664661410.247987642884254
53871STRdStriatum dorsal region0.1514430940151210.299682766199112
53871STRvStriatum ventral region0.1980712860822680.161987036466599
53871THThalamus0.1943577527999880.240892797708511
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
27039GO:0000004NDProcessbiological process unknown
27039GO:0005261IEAFunctioncation channel activity
27039GO:0005509IEAFunctioncalcium ion binding
27039GO:0005515NASFunctionprotein binding
27039GO:0006812IEAProcesscation transport
27039GO:0016020IEAComponentmembrane
27039GO:0016021TASComponentintegral to membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
27039IPR001682Ca/Na_poreCa2+/Na+ channel, pore region
27039IPR002111Cat_channel_TrpLCation (not K+) channel, TM region
27039IPR005821Ion_transIon transport
27039IPR013621Ion_trans_NIon transport N-terminal
27039IPR005820M+channel_nlgCation channel, non-ligand gated
27039IPR013122PKD1_2_channelPolycystin cation channel, PKD1/PKD2
27039IPR000434PKD_1Polycystic kidney disease type 1 protein
27039IPR003915PKD_2Polycystic kidney disease type 2 protein

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