Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2752
Official Symbol:GLUL
Other Aliases:GLNS|GS|PIG43
See related:HGNC:4341|MIM:138290|HPRD:00701
Chromosome:1
Location:1q31
Gene Description:glutamate-ammonia ligase (glutamine synthetase)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0302
ORGANISM:human
Entrez Gene ID:2752
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:14645
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14645CBCerebellum98.7665252685547100.0
14645CTXCerebral cortex100.0100.0
14645HIPHippocampal region100.0100.0
14645HPFHippocampal formation100.0100.0
14645HYHypothalamus100.0100.0
14645LSXLateral septal complex100.0100.0
14645MBMidbrain100.0100.0
14645MYMedulla100.0100.0
14645OLFOlfactory bulb100.0100.0
14645PPons100.0100.0
14645PALPallidum100.0100.0
14645RHPRetrohippocampal region100.0100.0
14645sAMYStriatum-like amygdalar nuclei100.0100.0
14645STRStriatum100.0100.0
14645STRdStriatum dorsal region100.0100.0
14645STRvStriatum ventral region100.0100.0
14645THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2752GO:0001505NRProcessregulation of neurotransmitter levels
2752GO:0004356IEAFunctionglutamate-ammonia ligase activity
2752GO:0006542IEAProcessglutamine biosynthesis
2752GO:0006807IEAProcessnitrogen compound metabolism
2752GO:0016874IEAFunctionligase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-8655NP_003737.1dynein light chain 1HPRD03334
NP_002056.28655-DLC1HPRD00701
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2752GLNA_HUMANP15104IPR008147Gln_synt_betaGlutamine synthetase, beta-Grasp
2752GLNA_HUMANP15104IPR008146Gln_synt_CGlutamine synthetase, catalytic region

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.