Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2767
Official Symbol:GNA11
Other Aliases:GNA-11
See related:HGNC:4379|MIM:139313|HPRD:00759
Chromosome:19
Location:19p13.3
Gene Description:guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0540
ORGANISM:human
Entrez Gene ID:2767
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:81662
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2767GO:0000166IEAFunctionnucleotide binding
2767GO:0003924TASFunctionGTPase activity
2767GO:0004871IEAFunctionsignal transducer activity
2767GO:0005525IEAFunctionGTP binding
2767GO:0005737TASComponentcytoplasm
2767GO:0005886TASComponentplasma membrane
2767GO:0006471IEAProcessprotein amino acid ADP-ribosylation
2767GO:0007165TASProcesssignal transduction
2767GO:0007186IEAProcessG-protein coupled receptor protein signaling pathway
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-3356NP_000612.15-hydroxytryptamine (serotonin) receptor 2AHPRD01638
-5739NP_000951.1prostaglandin I2 (prostacyclin) receptor (IP)HPRD08959
-4543NP_005949.1melatonin receptor 1AHPRD02812
-5998NP_652759.1regulator of G-protein signalling 3 isoform 6HPRD03720
NP_002058.1--Phosphoinositidase CHPRD00759
NP_002058.1--EDNRBHPRD00759
NP_002058.1--Trp3HPRD00759
NP_002058.1---BIND183184
NP_002058.15998-Regulator of G protein signaling 3HPRD00759
NP_002058.15739-Prostacyclin receptorHPRD00759
NP_002058.14543-Melatonin receptor 1AHPRD00759
NP_002058.13356-Serotonin 5-HT-2A receptorHPRD00759
NP_002058.17222NP_003296.1transient receptor potential cation channel, subfamily C, member 3HPRD15999
NP_002058.17222NP_003296.1transient receptor potential cation channel, subfamily C, member 3HPRD15999
NP_002058.16915NP_963998.1thromboxane A2 receptor isoform 2HPRD00759
NP_002058.16915NP_963998.1thromboxane A2 receptor isoform 2HPRD01768
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2767GNA11_HUMANP29992IPR002975Fungi_GproteinAFungal G-protein, alpha subunit
2767GNA11_HUMANP29992IPR000469Gprotein_alpha12G-protein alpha subunit, group 12
2767GNA11_HUMANP29992IPR000654Gprotein_alpha_QG-protein alpha subunit, group Q
2767GNA11_HUMANP29992IPR001019Gprotein_alph_bdGuanine nucleotide binding protein (G-protein), alpha subunit

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