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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry

For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information Gene ID: 2767 Official Symbol: GNA11 Other Aliases: GNA-11 See related: HGNC:4379|MIM:139313|HPRD:00759 Chromosome: 19 Location: 19p13.3 Gene Description: guanine nucleotide binding protein (G protein), alpha 11 (Gq class) Gene type: protein-coding Gene Structure: Genomic Context: KARG Evidence 1 KARG ID: EVIC0540 ORGANISM: human Entrez Gene ID: 2767 Evidence Type: Mapping from rat Evidence ID Type: Entrez Gene Evidence ID: 81662 Addiction Drug: Addiction Drug Detail: Addiction Brain Area: Drug Effects: Fold Change: Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas) Mouse Entrez Gene ID Brain Region Brain Region Detail Expression Level Expression Density Gene Ontology Gene ID GO ID Evidence GO Type GO Description 2767 GO:0000166 IEA Function nucleotide binding 2767 GO:0003924 TAS Function GTPase activity 2767 GO:0004871 IEA Function signal transducer activity 2767 GO:0005525 IEA Function GTP binding 2767 GO:0005737 TAS Component cytoplasm 2767 GO:0005886 TAS Component plasma membrane 2767 GO:0006471 IEA Process protein amino acid ADP-ribosylation 2767 GO:0007165 TAS Process signal transduction 2767 GO:0007186 IEA Process G-protein coupled receptor protein signaling pathway Interaction Information Gene Product ID Interactant Gene ID Interactant Gene Product ID Interactant Gene Product Name Source Source ID - 3356 NP_000612.1 5-hydroxytryptamine (serotonin) receptor 2A HPRD 01638 - 5739 NP_000951.1 prostaglandin I2 (prostacyclin) receptor (IP) HPRD 08959 - 4543 NP_005949.1 melatonin receptor 1A HPRD 02812 - 5998 NP_652759.1 regulator of G-protein signalling 3 isoform 6 HPRD 03720 NP_002058.1 - - Phosphoinositidase C HPRD 00759 NP_002058.1 - - EDNRB HPRD 00759 NP_002058.1 - - Trp3 HPRD 00759 NP_002058.1 - - - BIND 183184 NP_002058.1 5998 - Regulator of G protein signaling 3 HPRD 00759 NP_002058.1 5739 - Prostacyclin receptor HPRD 00759 NP_002058.1 4543 - Melatonin receptor 1A HPRD 00759 NP_002058.1 3356 - Serotonin 5-HT-2A receptor HPRD 00759 NP_002058.1 7222 NP_003296.1 transient receptor potential cation channel, subfamily C, member 3 HPRD 15999 NP_002058.1 7222 NP_003296.1 transient receptor potential cation channel, subfamily C, member 3 HPRD 15999 NP_002058.1 6915 NP_963998.1 thromboxane A2 receptor isoform 2 HPRD 00759 NP_002058.1 6915 NP_963998.1 thromboxane A2 receptor isoform 2 HPRD 01768 Domain Information Gene ID Uniprot/Swissprot ID Uniprot/Swissprot ACC Interpro ID Interpro Short Description Interpro Long Description 2767 GNA11_HUMAN P29992 IPR002975 Fungi_GproteinA Fungal G-protein, alpha subunit 2767 GNA11_HUMAN P29992 IPR000469 Gprotein_alpha12 G-protein alpha subunit, group 12 2767 GNA11_HUMAN P29992 IPR000654 Gprotein_alpha_Q G-protein alpha subunit, group Q 2767 GNA11_HUMAN P29992 IPR001019 Gprotein_alph_bd Guanine nucleotide binding protein (G-protein), alpha subunit © Center for Bioinformatics(CBI), Peking University Any Comments and suggestions to : KARG GROUP.