Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2805
Official Symbol:GOT1
Other Aliases:GIG18
See related:HGNC:4432|MIM:138180|HPRD:00687
Chromosome:10
Location:10q24.1-q25.1
Gene Description:glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0549
ORGANISM:human
Entrez Gene ID:2805
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24401
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14718CBCerebellum80.6285247802734100.0
14718CTXCerebral cortex100.0100.0
14718HIPHippocampal region100.0100.0
14718HPFHippocampal formation100.0100.0
14718HYHypothalamus100.0100.0
14718LSXLateral septal complex100.0100.0
14718MBMidbrain100.0100.0
14718MYMedulla100.0100.0
14718OLFOlfactory bulb100.0100.0
14718PPons100.0100.0
14718PALPallidum100.0100.0
14718RHPRetrohippocampal region100.0100.0
14718sAMYStriatum-like amygdalar nuclei100.0100.0
14718STRStriatum100.0100.0
14718STRdStriatum dorsal region100.0100.0
14718STRvStriatum ventral region100.0100.0
14718THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2805GO:0004069IEAFunctionaspartate transaminase activity
2805GO:0005829NRComponentcytosol
2805GO:0006520IEAProcessamino acid metabolism
2805GO:0006533TASProcessaspartate catabolism
2805GO:0009058IEAProcessbiosynthesis
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2805AATC_HUMANP17174IPR004839Aminotrans_I/IIAminotransferase, class I and II
2805AATC_HUMANP17174IPR000796Asp_transAspartate/other aminotransferase
2805AATC_HUMANP17174IPR004838NHtransf_1_BSAminotransferases class-I pyridoxal-phosphate-binding site

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