Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2823
Official Symbol:GPM6A
Other Aliases:GPM6|M6A
See related:HGNC:4460|MIM:601275|HPRD:03174
Chromosome:4
Location:4q34
Gene Description:glycoprotein M6A
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0130
ORGANISM:human
Entrez Gene ID:2823
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12629581
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Dorsolateral Prefrontal Cortex
Drug Effects:Upregulated/Downregulated
Fold Change:3.25 :: 2.96 :: 2.84 :: 1.91 :: -1.59 :: -3.48 :: 2.42
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
234267CBCerebellum100.0100.0
234267CTXCerebral cortex100.0100.0
234267HIPHippocampal region100.0100.0
234267HPFHippocampal formation100.0100.0
234267HYHypothalamus100.0100.0
234267LSXLateral septal complex100.0100.0
234267MBMidbrain100.0100.0
234267MYMedulla94.5849227905273100.0
234267OLFOlfactory bulb100.0100.0
234267PPons94.8654022216797100.0
234267PALPallidum100.0100.0
234267RHPRetrohippocampal region100.0100.0
234267sAMYStriatum-like amygdalar nuclei100.0100.0
234267STRStriatum100.0100.0
234267STRdStriatum dorsal region100.0100.0
234267STRvStriatum ventral region100.0100.0
234267THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2823GO:0005887NRComponentintegral to plasma membrane
2823GO:0009986IEPComponentcell surface
2823GO:0016020IEAComponentmembrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2823GPM6A_HUMANP51674IPR000870Homoser_kinHomoserine kinase
2823GPM6A_HUMANP51674IPR001614Myelin_PLPMyelin proteolipid protein PLP

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