Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:288
Official Symbol:ANK3
Other Aliases:ANKYRIN-G|FLJ45464
See related:HGNC:494|MIM:600465|HPRD:02715
Chromosome:10
Location:10q21
Gene Description:ankyrin 3, node of Ranvier (ankyrin G)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0121
ORGANISM:human
Entrez Gene ID:288
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:11735
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
11735CBCerebellum100.0100.0
11735CTXCerebral cortex100.0100.0
11735HIPHippocampal region100.0100.0
11735HPFHippocampal formation100.0100.0
11735HYHypothalamus100.0100.0
11735LSXLateral septal complex100.0100.0
11735MBMidbrain100.0100.0
11735MYMedulla83.0103187561035100.0
11735OLFOlfactory bulb100.0100.0
11735PPons93.2758979797363100.0
11735PALPallidum100.0100.0
11735RHPRetrohippocampal region100.0100.0
11735sAMYStriatum-like amygdalar nuclei100.0100.0
11735STRStriatum100.0100.0
11735STRdStriatum dorsal region100.0100.0
11735STRvStriatum ventral region100.0100.0
11735THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
288GO:0005200NRFunctionstructural constituent of cytoskeleton
288GO:0005515IEAFunctionprotein binding
288GO:0005554NDFunctionmolecular function unknown
288GO:0005783TASComponentendoplasmic reticulum
288GO:0005794TASComponentGolgi apparatus
288GO:0005856IEAComponentcytoskeleton
288GO:0005856NRComponentcytoskeleton
288GO:0006605NASProcessprotein targeting
288GO:0007016TASProcesscytoskeletal anchoring
288GO:0007165IEAProcesssignal transduction
288GO:0008372NDComponentcellular component unknown
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-6324NP_001028.1sodium channel, voltage-gated, type I, beta isoform aHPRD02581
-3746NP_004967.1Shaw-related voltage-gated potassium channel protein 1HPRD15936
-57731NP_066022.1spectrin, beta, non-erythrocytic 4 isoform 1HPRD09372
NP_066267.2--Beta 4 spectrinHPRD02715
NP_066267.2--Nav1.2aHPRD02715
NP_066267.2--Kv3.1bHPRD02715
NP_066267.2--Kv3.2HPRD02715
NP_066267.257731-Spectrin beta IVHPRD02715
NP_066267.26324-Sodium channel, voltage gated, type 1, beta subunitHPRD02715
NP_066267.23747-KCNC2HPRD02715
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
288IPR000488DeathDeath
288IPR000906ZU5ZU5
288ANK3_HUMANQ12955IPR002110ANKAnkyrin
288ANK3_HUMANQ12955IPR000488DeathDeath
288ANK3_HUMANQ12955IPR013555TRP_2Transient receptor ion channel II
288ANK3_HUMANQ12955IPR000906ZU5ZU5

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