Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:28951
Official Symbol:TRIB2
Other Aliases:GS3955|TRB2
See related:HGNC:30809|HPRD:18224
Chromosome:2
Location:2p25.1-p24.3
Gene Description:tribbles homolog 2 (Drosophila)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0097
ORGANISM:human
Entrez Gene ID:28951
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:217410
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
217410CBCerebellum14.087392807006839.4649381637573
217410CTXCerebral cortex36.273547172546432.3397665023804
217410HIPHippocampal region17.584503650665326.6863493919373
217410HPFHippocampal formation27.024991035461437.0800514221191
217410HYHypothalamus12.078710079193110.1014708280563
217410LSXLateral septal complex36.28926301002531.0109150409698
217410MBMidbrain12.686678946018212.6187843084335
217410MYMedulla19.964772462844824.4368646144867
217410OLFOlfactory bulb20.514902114868217.9180941581726
217410PPons10.341813921928412.4053189754486
217410PALPallidum24.88217806816124.3808717727661
217410RHPRetrohippocampal region42.080732345581150.7172565460205
217410sAMYStriatum-like amygdalar nuclei23.890511035919219.5524592399597
217410STRStriatum37.461606025695830.3814725875854
217410STRdStriatum dorsal region40.510972976684632.5639839172363
217410STRvStriatum ventral region40.436540603637732.2243719100952
217410THThalamus21.507366895675718.8908308744431
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
28951GO:0000166ISSFunctionnucleotide binding
28951GO:0004672ISSFunctionprotein kinase activity
28951GO:0004860IEAFunctionprotein kinase inhibitor activity
28951GO:0005524IEAFunctionATP binding
28951GO:0005737ISSComponentcytoplasm
28951GO:0006468ISSProcessprotein amino acid phosphorylation
28951GO:0043405ISSProcessregulation of MAPK activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
28951TRIB2_HUMANQ92519IPR013543CaMKII_ADCalcium/calmodulin dependent protein kinase II, association-domain
28951TRIB2_HUMANQ92519IPR000719Prot_kinaseProtein kinase
28951TRIB2_HUMANQ92519IPR013695WAKWall-associated kinase

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