Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2905
Official Symbol:GRIN2C
Other Aliases:NMDAR2C|NR2C
See related:HGNC:4587|MIM:138254|HPRD:00699
Chromosome:17
Location:17q25
Gene Description:glutamate receptor, ionotropic, N-methyl D-aspartate 2C
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0515
ORGANISM:human
Entrez Gene ID:2905
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24411
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14813CBCerebellum100.0100.0
14813CTXCerebral cortex17.19384407997137.24609506130219
14813HIPHippocampal region23.07190084457412.6344308853149
14813HPFHippocampal formation22.70024967193611.25346326828
14813HYHypothalamus2.06696641445161.54608255624771
14813LSXLateral septal complex22.9452416896828.6285947561264
14813MBMidbrain4.337139368057252.82762879133224
14813MYMedulla16.211410522460917.8607168197632
14813OLFOlfactory bulb51.881994247436532.5646419525146
14813PPons10.3977524042137.38235998153687
14813PALPallidum9.618039846420295.73071503639221
14813RHPRetrohippocampal region22.36328792572029.4610915184021
14813sAMYStriatum-like amygdalar nuclei11.1385810971264.08952867984772
14813STRStriatum19.61074161529548.50610017776489
14813STRdStriatum dorsal region19.92555737495429.34909629821777
14813STRvStriatum ventral region22.744494676598.44793063402176
14813THThalamus61.371034622192442.0988073348999
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2905GO:0000287IEAFunctionmagnesium ion binding
2905GO:0004872IEAFunctionreceptor activity
2905GO:0004972TASFunctionN-methyl-D-aspartate selective glutamate receptor activity
2905GO:0005215IEAFunctiontransporter activity
2905GO:0005216IEAFunctionion channel activity
2905GO:0005234IEAFunctionglutamate-gated ion channel activity
2905GO:0005509IEAFunctioncalcium ion binding
2905GO:0005887TASComponentintegral to plasma membrane
2905GO:0006811IEAProcession transport
2905GO:0007215TASProcessglutamate signaling pathway
2905GO:0045211IEAComponentpostsynaptic membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-3603AAQ86961.1Homo sapiens neural interleukin 16 precursor protein mRNA, complete cds.HPRD04329
-10207NP_733750.2InaD-like protein isoform 1HPRD04434
NP_000826.1--CIPPHPRD00699
NP_000826.13603-Interleukin 16HPRD00699
NP_000826.1155871NP_057853.1Tat--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2905NMDE3_HUMANQ14957IPR001828ANF_lig_bd_rcptExtracellular ligand-binding receptor
2905NMDE3_HUMANQ14957IPR001311glu_rcpt_sol_bdSolute-binding protein/glutamate receptor
2905NMDE3_HUMANQ14957IPR001320Iontro_glu_rcptIonotropic glutamate receptor
2905NMDE3_HUMANQ14957IPR001508NMDA_rcptNMDA receptor
2905NMDE3_HUMANQ14957IPR000694PRO_richProline-rich region

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.