Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2907
Official Symbol:GRINA
Other Aliases:HNRGW|MGC99687|NMDARA1|TMBIM3
See related:HGNC:4589|MIM:138251|HPRD:15927
Chromosome:8
Location:8q24.3
Gene Description:glutamate receptor, ionotropic, N-methyl D-asparate-associated protein 1 (glutamate binding)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0481
ORGANISM:human
Entrez Gene ID:2907
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:266668
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIM0332
ORGANISM:human
Entrez Gene ID:2907
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Upregulated
Fold Change:0.59
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
66168CBCerebellum65.747156143188560.7440605163574
66168CTXCerebral cortex72.34601974487362.625599861145
66168HIPHippocampal region75.129470825195363.5320901870728
66168HPFHippocampal formation77.777406692504967.1089515686035
66168HYHypothalamus69.770792007446360.3753318786621
66168LSXLateral septal complex57.366969585418753.3242285251617
66168MBMidbrain65.702911376953159.7710618972778
66168MYMedulla72.943914413452165.6521778106689
66168OLFOlfactory bulb77.762569427490265.5484771728516
66168PPons71.989046096801866.7364921569824
66168PALPallidum63.866580009460459.1414709091187
66168RHPRetrohippocampal region83.374874114990273.0124320983887
66168sAMYStriatum-like amygdalar nuclei63.025771141052256.2950353622437
66168STRStriatum59.202816963195854.1853938102722
66168STRdStriatum dorsal region58.606382369995153.7735621929169
66168STRvStriatum ventral region60.737754821777355.0861783027649
66168THThalamus70.31197547912661.3989133834839
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2907GO:0004872IEAFunctionreceptor activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2907IPR006030Mollsc_rhodpsn_CMolluscan rhodopsin C-terminal tail
2907IPR000694PRO_richProline-rich region
2907IPR006214UPF0005Protein of unknown function UPF0005

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