Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:29114
Official Symbol:TAGLN3
Other Aliases:NP22|NP25
See related:HGNC:29868|MIM:607953|HPRD:12136
Chromosome:3
Location:3q13.2
Gene Description:transgelin 3
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0122
ORGANISM:human
Entrez Gene ID:29114
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12629581
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Dorsolateral Prefrontal Cortex
Drug Effects:Upregulated/Downregulated
Fold Change:1.38 :: 1.05 :: 1.34 :: 1.45 :: -1.63 :: -1.39 :: -3.27
KARG Evidence 2
KARG ID:EVIP0262
ORGANISM:human
Entrez Gene ID:29114
Evidence Type:Proteomics
Evidence ID Type:PUBMED
Evidence ID:16172612
Addiction Drug:ALCOHOL
Addiction Drug Detail:Chronic alcohol use
Addiction Brain Area:Brain
Drug Effects:Downregulated
Fold Change:-2.1::-2.8
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
56370CBCerebellum54.17589569091873.9578132629395
56370CTXCerebral cortex100.0100.0
56370HIPHippocampal region80.0953636169434100.0
56370HPFHippocampal formation90.0409622192383100.0
56370HYHypothalamus100.0100.0
56370LSXLateral septal complex96.9820671081543100.0
56370MBMidbrain94.8059043884277100.0
56370MYMedulla87.0608673095703100.0
56370OLFOlfactory bulb94.2695693969727100.0
56370PPons85.8492774963379100.0
56370PALPallidum91.971042633056694.0943412780762
56370RHPRetrohippocampal region100.0100.0
56370sAMYStriatum-like amygdalar nuclei89.195346832275491.2581253051758
56370STRStriatum73.207386016845754.4350891113281
56370STRdStriatum dorsal region58.789011001586937.0074615478516
56370STRvStriatum ventral region68.562965393066448.901876449585
56370THThalamus94.7505493164062100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
29114GO:0007417TASProcesscentral nervous system development
29114GO:0007517IEAProcessmuscle development
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
29114TAGL3_HUMANQ9UI15IPR001997CalponinCalponin
29114TAGL3_HUMANQ9UI15IPR001715Calponin_act_bdCalponin-like actin-binding
29114TAGL3_HUMANQ9UI15IPR000557Calponin_repeatCalponin repeat
29114TAGL3_HUMANQ9UI15IPR003096SM22_calponinSM22/calponin
29114TAGL3_HUMANQ9UI15IPR001061TransgelinTransgelin (SM22-alpha)

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.