Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2937
Official Symbol:GSS
Other Aliases:GSHS|MGC14098
See related:HGNC:4624|MIM:601002|HPRD:03000
Chromosome:20
Location:20q11.2
Gene Description:glutathione synthetase
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0206
ORGANISM:human
Entrez Gene ID:2937
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:14854
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14854CBCerebellum10.856135368347211.2921423912048
14854CTXCerebral cortex6.788777470588685.00869846343994
14854HIPHippocampal region15.698586463928216.6246604919434
14854HPFHippocampal formation11.779900074005111.0668458938599
14854HYHypothalamus3.181264102458952.70770055055618
14854LSXLateral septal complex2.135207474231721.57502394914627
14854MBMidbrain4.924604535102844.59172117710114
14854MYMedulla12.505145549774214.0447869300842
14854OLFOlfactory bulb6.679505109786994.88104927539825
14854PPons11.219788551330612.1025757789612
14854PALPallidum8.033042550086987.51227843761444
14854RHPRetrohippocampal region6.611776947975164.85719299316406
14854sAMYStriatum-like amygdalar nuclei3.225039601325992.69849860668182
14854STRStriatum4.354748129844673.34659969806671
14854STRdStriatum dorsal region4.929277777671813.85908901691437
14854STRvStriatum ventral region3.8880038857462.71707659959793
14854THThalamus34.472956657409732.4294385910034
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2937GO:0000166IEAFunctionnucleotide binding
2937GO:0004363TASFunctionglutathione synthase activity
2937GO:0005524IEAFunctionATP binding
2937GO:0006520TASProcessamino acid metabolism
2937GO:0006750IEAProcessglutathione biosynthesis
2937GO:0006979TASProcessresponse to oxidative stress
2937GO:0007399TASProcessnervous system development
2937GO:0016874IEAFunctionligase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_000169.1155871NP_057853.1Tat--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2937GSHB_HUMANP48637IPR004887GSH_synthase_eukEukaryotic glutathione synthase
2937GSHB_HUMANP48637IPR005615GSH_synth_ATP_bdEukaryotic glutathione synthase, ATP-binding

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