Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:29767
Official Symbol:TMOD2
Other Aliases:MGC39481|NTMOD
See related:HGNC:11872|MIM:602928|HPRD:04237
Chromosome:15
Location:15q21.1-q21.2
Gene Description:tropomodulin 2 (neuronal)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0539
ORGANISM:human
Entrez Gene ID:29767
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:58814
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:QTL0137
ORGANISM:human
Entrez Gene ID:29767
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 3
KARG ID:QTL0138
ORGANISM:human
Entrez Gene ID:29767
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
50876CBCerebellum93.7766265869141100.0
50876CTXCerebral cortex100.0100.0
50876HIPHippocampal region100.0100.0
50876HPFHippocampal formation100.0100.0
50876HYHypothalamus100.0100.0
50876LSXLateral septal complex100.0100.0
50876MBMidbrain100.0100.0
50876MYMedulla100.0100.0
50876OLFOlfactory bulb100.0100.0
50876PPons100.0100.0
50876PALPallidum100.0100.0
50876RHPRetrohippocampal region100.0100.0
50876sAMYStriatum-like amygdalar nuclei100.0100.0
50876STRStriatum100.0100.0
50876STRdStriatum dorsal region100.0100.0
50876STRvStriatum ventral region100.0100.0
50876THThalamus100.0100.0
KARG Evidence 4
KARG ID:QTL0137
Trait:differences in cocaine responsiveness
Peak:38
Peak Marker:Emv-3
Parents:C57BL/6J x DBA/2J intercross
Evidence ID:7932176
KARG Evidence 5
KARG ID:QTL0138
Trait:differences in cocaine responsiveness
Peak:38
Peak Marker:d
Parents:C57BL/6J x DBA/2J intercross
Evidence ID:7932176
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
29767GO:0003779IEAFunctionactin binding
29767GO:0005523TASFunctiontropomyosin binding
29767GO:0005856IEAComponentcytoskeleton
29767GO:0007399TASProcessnervous system development
29767GO:0008290NRComponentF-actin capping protein complex
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_055363.1--TM-2HPRD04237
NP_055363.1--TM-5HPRD04237
NP_055363.1--TMBr-3HPRD04237
NP_055363.1--TPM4HPRD04237
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
29767TMOD2_HUMANQ9NZR1IPR007091LRR_RNinhLeucine-rich repeat, ribonuclease inhibitor type
29767TMOD2_HUMANQ9NZR1IPR004934TropomodulinTropomodulin

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