Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry

For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information Gene ID: 3035 Official Symbol: HARS Other Aliases: FLJ20491|HRS See related: HGNC:4816|MIM:142810|HPRD:00827 Chromosome: 5 Location: 5q31.3 Gene Description: histidyl-tRNA synthetase Gene type: protein-coding Gene Structure: Genomic Context: KARG Evidence 1 KARG ID: EVIC0288 ORGANISM: human Entrez Gene ID: 3035 Evidence Type: Mapping from mouse Evidence ID Type: Entrez Gene Evidence ID: 15115 Addiction Drug: Addiction Drug Detail: Addiction Brain Area: Drug Effects: Fold Change: Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas) Mouse Entrez Gene ID Brain Region Brain Region Detail Expression Level Expression Density 15115 CB Cerebellum 3.22681760787964 3.86188489198685 15115 CTX Cerebral cortex 1.22596397995949 0.845817565917969 15115 HIP Hippocampal region 9.2422730922699 5.47495746612549 15115 HPF Hippocampal formation 6.13682377338409 3.56920003890991 15115 HY Hypothalamus 0.689748756587505 0.519585080444813 15115 LSX Lateral septal complex 0.254161514341831 0.25196024030447 15115 MB Midbrain 0.847391426563263 0.855432763695717 15115 MY Medulla 5.73535847663879 6.38837730884552 15115 OLF Olfactory bulb 4.63695019483566 2.73818761110306 15115 P Pons 5.14903062582016 5.37488281726837 15115 PAL Pallidum 1.74045664072037 1.41259455680847 15115 RHP Retrohippocampal region 1.67571993172169 1.27147860825062 15115 sAMY Striatum-like amygdalar nuclei 0.903575077652931 0.57646544277668 15115 STR Striatum 0.508570678532124 0.351472601294518 15115 STRd Striatum dorsal region 0.423740848898888 0.299974344670773 15115 STRv Striatum ventral region 0.630051702260971 0.408337719738483 15115 TH Thalamus 0.806689094752073 0.556032367050648 Gene Ontology Gene ID GO ID Evidence GO Type GO Description 3035 GO:0000166 IEA Function nucleotide binding 3035 GO:0004821 NAS Function histidine-tRNA ligase activity 3035 GO:0005524 NAS Function ATP binding 3035 GO:0005737 NAS Component cytoplasm 3035 GO:0006412 NAS Process protein biosynthesis 3035 GO:0006427 IEA Process histidyl-tRNA aminoacylation 3035 GO:0016874 IEA Function ligase activity Interaction Information Gene Product ID Interactant Gene ID Interactant Gene Product ID Interactant Gene Product Name Source Source ID - 6125 NP_000960.2 ribosomal protein L5 HPRD 04699 - 6897 NP_689508.3 threonyl-tRNA synthetase HPRD 01762 NP_002100.2 - - Elongation factor beta HPRD 00827 NP_002100.2 - - Elongation factor gamma HPRD 00827 NP_002100.2 6125 - Ribosomal protein L5 HPRD 00827 NP_002100.2 6897 - Threonyl tRNA synthetase HPRD 00827 Domain Information Gene ID Uniprot/Swissprot ID Uniprot/Swissprot ACC Interpro ID Interpro Short Description Interpro Long Description 3035 SYH_HUMAN P12081 IPR004154 Anticodon_bd Anticodon-binding 3035 SYH_HUMAN P12081 IPR002314 tRNA-synt_2b tRNA synthetase, class II (G, H, P and S) 3035 SYH_HUMAN P12081 IPR006195 tRNA_ligase_II Aminoacyl-transfer RNA synthetase, class II 3035 SYH_HUMAN P12081 IPR000738 WHEP-TRS WHEP-TRS © Center for Bioinformatics(CBI), Peking University Any Comments and suggestions to : KARG GROUP.