Basic Information | Gene ID: | 3035 | Official Symbol: | HARS | Other Aliases: | FLJ20491|HRS | See related: | HGNC:4816|MIM:142810|HPRD:00827 | Chromosome: | 5 | Location: | 5q31.3 | Gene Description: | histidyl-tRNA synthetase | Gene type: | protein-coding | Gene Structure: |  | Genomic Context: |  |
KARG Evidence 1 | KARG ID: | EVIC0288 | ORGANISM: | human | Entrez Gene ID: | 3035 | Evidence Type: | Mapping from mouse | Evidence ID Type: | Entrez Gene | Evidence ID: | 15115 | Addiction Drug: | | Addiction Drug Detail: | | Addiction Brain Area: | | Drug Effects: | | Fold Change: | |
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas) | Mouse Entrez Gene ID | Brain Region | Brain Region Detail | Expression Level | Expression Density | 15115 | CB | Cerebellum | 3.22681760787964 | 3.86188489198685 | 15115 | CTX | Cerebral cortex | 1.22596397995949 | 0.845817565917969 | 15115 | HIP | Hippocampal region | 9.2422730922699 | 5.47495746612549 | 15115 | HPF | Hippocampal formation | 6.13682377338409 | 3.56920003890991 | 15115 | HY | Hypothalamus | 0.689748756587505 | 0.519585080444813 | 15115 | LSX | Lateral septal complex | 0.254161514341831 | 0.25196024030447 | 15115 | MB | Midbrain | 0.847391426563263 | 0.855432763695717 | 15115 | MY | Medulla | 5.73535847663879 | 6.38837730884552 | 15115 | OLF | Olfactory bulb | 4.63695019483566 | 2.73818761110306 | 15115 | P | Pons | 5.14903062582016 | 5.37488281726837 | 15115 | PAL | Pallidum | 1.74045664072037 | 1.41259455680847 | 15115 | RHP | Retrohippocampal region | 1.67571993172169 | 1.27147860825062 | 15115 | sAMY | Striatum-like amygdalar nuclei | 0.903575077652931 | 0.57646544277668 | 15115 | STR | Striatum | 0.508570678532124 | 0.351472601294518 | 15115 | STRd | Striatum dorsal region | 0.423740848898888 | 0.299974344670773 | 15115 | STRv | Striatum ventral region | 0.630051702260971 | 0.408337719738483 | 15115 | TH | Thalamus | 0.806689094752073 | 0.556032367050648 |
Gene Ontology | Gene ID | GO ID | Evidence | GO Type | GO Description | 3035 | GO:0000166 | IEA | Function | nucleotide binding | 3035 | GO:0004821 | NAS | Function | histidine-tRNA ligase activity | 3035 | GO:0005524 | NAS | Function | ATP binding | 3035 | GO:0005737 | NAS | Component | cytoplasm | 3035 | GO:0006412 | NAS | Process | protein biosynthesis | 3035 | GO:0006427 | IEA | Process | histidyl-tRNA aminoacylation | 3035 | GO:0016874 | IEA | Function | ligase activity |
Interaction Information | Gene Product ID | Interactant Gene ID | Interactant Gene Product ID | Interactant Gene Product Name | Source | Source ID | - | 6125 | NP_000960.2 | ribosomal protein L5 | HPRD | 04699 | - | 6897 | NP_689508.3 | threonyl-tRNA synthetase | HPRD | 01762 | NP_002100.2 | - | - | Elongation factor beta | HPRD | 00827 | NP_002100.2 | - | - | Elongation factor gamma | HPRD | 00827 | NP_002100.2 | 6125 | - | Ribosomal protein L5 | HPRD | 00827 | NP_002100.2 | 6897 | - | Threonyl tRNA synthetase | HPRD | 00827 |
Domain Information | Gene ID | Uniprot/Swissprot ID | Uniprot/Swissprot ACC | Interpro ID | Interpro Short Description | Interpro Long Description | 3035 | SYH_HUMAN | P12081 | IPR004154 | Anticodon_bd | Anticodon-binding | 3035 | SYH_HUMAN | P12081 | IPR002314 | tRNA-synt_2b | tRNA synthetase, class II (G, H, P and S) | 3035 | SYH_HUMAN | P12081 | IPR006195 | tRNA_ligase_II | Aminoacyl-transfer RNA synthetase, class II | 3035 | SYH_HUMAN | P12081 | IPR000738 | WHEP-TRS | WHEP-TRS |
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