Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:30948
Official Symbol:Bin1
Other Aliases:ALP-1|Amphl|BRAMP-2|SH3P9
See related:MGI:108092
Chromosome:18
Location:18 B1|18 14.0 cM
Gene Description:bridging integrator 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0511
ORGANISM:mouse
Entrez Gene ID:30948
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15745951
Addiction Drug:ALCOHOL
Addiction Drug Detail:ACUTE ETHANOL ADMINISTRATION
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Upregulated
Fold Change:2.45
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
30948GO:0005515IEAFunctionprotein binding
30948GO:0005634IEAComponentnucleus
30948GO:0005737IEAComponentcytoplasm
30948GO:0006897IEAProcessendocytosis
30948GO:0007049IEAProcesscell cycle
30948GO:0007275IEAProcessdevelopment
30948GO:0030100IEAProcessregulation of endocytosis
30948GO:0030154IEAProcesscell differentiation
30948GO:0045786IEAProcessnegative regulation of progression through cell cycle
30948GO:0048488RCAProcesssynaptic vesicle endocytosis
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_033798.154673AAL59846.1Mus musculus endophilin B1b mRNA, complete cdsBIND153577
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
30948BIN1_MOUSEO08539IPR003005AmphiphysinAmphiphysin
30948BIN1_MOUSEO08539IPR003023Amphiphysin_2Amphiphysin, isoform 2
30948BIN1_MOUSEO08539IPR004148BARBAR
30948BIN1_MOUSEO08539IPR000875CecropinCecropin
30948BIN1_MOUSEO08539IPR000108Neu_cyt_fact_2Neutrophil cytosol factor 2
30948BIN1_MOUSEO08539IPR000694PRO_richProline-rich region
30948BIN1_MOUSEO08539IPR001452SH3Src homology-3
30948BIN1_MOUSEO08539IPR011511SH3_2Variant SH3

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