Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3107
Official Symbol:HLA-C
Other Aliases:Cw*1701|D6S204|FLJ27082|HLA-JY3|HLC-C
See related:HGNC:4933|MIM:142840|HPRD:00829
Chromosome:6
Location:6p21.3
Gene Description:major histocompatibility complex, class I, C
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0002
ORGANISM:human
Entrez Gene ID:3107
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:14964
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3107GO:0005887NASComponentintegral to plasma membrane
3107GO:0016020IEAComponentmembrane
3107GO:0016021IEAComponentintegral to membrane
3107GO:0019882IEAProcessantigen presentation
3107GO:0019883IEAProcessantigen presentation, endogenous antigen
3107GO:0019885IEAProcessantigen processing, endogenous antigen via MHC class I
3107GO:0030106IEAFunctionMHC class I receptor activity
3107GO:0030106NASFunctionMHC class I receptor activity
3107GO:0042612IEAComponentMHC class I protein complex
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_002108.3--HP-3E4 NK receptorHPRD00829
NP_002108.3--KIR2DL3HPRD00829
NP_002108.3--TapasinHPRD00829
NP_002108.3--KIR-K6HPRD00829
NP_002108.3--KIR-K7HPRD00829
NP_002108.3--KIR2DL1HPRD00829
NP_002108.3--KIR2DL2HPRD00829
NP_002108.3--KIR2DL1HPRD00829
NP_002108.3--ILT4HPRD00829
NP_002108.3--T cell receptorHPRD00829
NP_002108.36891NP_000535.2transporter 2, ATP-binding cassette, sub-family B isoform 1HPRD00829
NP_002108.33309NP_005338.1heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)HPRD00682
NP_002108.33309NP_005338.1heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)HPRD00829
NP_002108.310288NP_005865.1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2HPRD11994
NP_002108.310859NP_006660.1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1HPRD07273
NP_002108.310859NP_006660.1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1HPRD00829
NP_002108.33802NP_055033.1killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1HPRD12000
NP_002108.33803NP_055034.1killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2HPRD16080
NP_002108.33806NP_055327.1killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1HPRD00829
NP_002108.33806NP_055327.1killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1HPRD05384
NP_002108.33804NP_056952.1killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 isoform 2HPRD10383
NP_002108.3155871NP_057853.1Tat--
NP_002108.3155871NP_057853.1Tat--
NP_002108.3155945NP_057855.1Vpu--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
31071C07_HUMANP10321IPR007110Ig-likeImmunoglobulin-like
31071C07_HUMANP10321IPR003597Ig_c1Immunoglobulin C1 type
31071C07_HUMANP10321IPR013151ImmunoglobulinImmunoglobulin
31071C07_HUMANP10321IPR001039MHC_I_alpha_A1A2MHC class I, alpha chain, alpha1 and alpha2
31071C07_HUMANP10321IPR010579MHC_I_alpha_CMHC class I, alpha chain, C-terminal
31071C17_HUMANQ95604IPR007110Ig-likeImmunoglobulin-like
31071C17_HUMANQ95604IPR003597Ig_c1Immunoglobulin C1 type
31071C17_HUMANQ95604IPR013151ImmunoglobulinImmunoglobulin
31071C17_HUMANQ95604IPR001039MHC_I_alpha_A1A2MHC class I, alpha chain, alpha1 and alpha2
31071C17_HUMANQ95604IPR010579MHC_I_alpha_CMHC class I, alpha chain, C-terminal

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