Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3280
Official Symbol:HES1
Other Aliases:FLJ20408|HES-1|HHL|HRY
See related:HGNC:5192|MIM:139605|HPRD:00770
Chromosome:3
Location:3q28-q29
Gene Description:hairy and enhancer of split 1, (Drosophila)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0413
ORGANISM:human
Entrez Gene ID:3280
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:29577
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3280GO:0003677TASFunctionDNA binding
3280GO:0005634IEAComponentnucleus
3280GO:0006355IEAProcessregulation of transcription, DNA-dependent
3280GO:0007399TASProcessnervous system development
3280GO:0030528IEAFunctiontranscription regulator activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-7088NP_005068.2transducin-like enhancer protein 1HPRD02557
-55502NP_061115.2hairy and enhancer of split 6HPRD11021
NC_000003.93516--BIND183953
NC_000003.95430NP_000928.1DNA directed RNA polymerase II polypeptide ABIND184979
NC_000003.93280NP_005515.1hairy and enhancer of split 1BIND183955
NC_000003.911198NP_009123.1chromatin-specific transcription elongation factor large subunitBIND183954
NP_005515.17088-TLE1HPRD00770
NP_005515.123411NP_036370.2sirtuin 1HPRD08381
NP_005515.123411NP_036370.2sirtuin 1HPRD00770
NP_005515.123493NP_036391.1hairy/enhancer-of-split related with YRPW motif 2HPRD00770
NP_005515.123493NP_036391.1hairy/enhancer-of-split related with YRPW motif 2HPRD05243
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3280HES1_HUMANQ14469IPR001092HLH_basicBasic helix-loop-helix dimerisation region bHLH
3280HES1_HUMANQ14469IPR003650OrangeOrange
3280HES1_HUMANQ14469IPR000694PRO_richProline-rich region

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.