Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3303
Official Symbol:HSPA1A
Other Aliases:HSP70-1|HSP72|HSPA1|HSPA1B
See related:HGNC:5232|MIM:140550|HPRD:00774
Chromosome:6
Location:6p21.3
Gene Description:heat shock 70kDa protein 1A
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0415
ORGANISM:human
Entrez Gene ID:3303
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:294254
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3303GO:0000166IEAFunctionnucleotide binding
3303GO:0005524IEAFunctionATP binding
3303GO:0006457IEAProcessprotein folding
3303GO:0006986IEAProcessresponse to unfolded protein
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-7157NP_000537.2tumor protein p53HPRD01859
-9531NP_004272.2BCL2-associated athanogene 3HPRD04860
-9532NP_004273.1BCL2-associated athanogene 2HPRD04859
-9530NP_004865.1BCL2-associated athanogene 4HPRD04861
-3337NP_006136.1DnaJ (Hsp40) homolog, subfamily B, member 1HPRD05198
-10963NP_006810.1stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein)HPRD05454
-9868NP_055635.3translocase of outer mitochondrial membrane 70 homolog AHPRD16194
-8805NP_056989.2transcriptional intermediary factor 1 alpha isoform aHPRD04556
-51726NP_057390.1DnaJ (Hsp40) homolog, subfamily B, member 11 precursorHPRD07485
NP_005336.2--Cdk9HPRD00774
NP_005336.2--DnaJHPRD00774
NP_005336.2--RAP46HPRD00774
NP_005336.2--Tid-1HPRD00774
NP_005336.2--Protein Kinase CHPRD00774
NP_005336.2--HRIHPRD00774
NP_005336.2--Tom70HPRD00774
NP_005336.27157-p53HPRD00774
NP_005336.29531-BCL2 associated athanogene 3HPRD00774
NP_005336.29532-BCL2 associated athanogene 2HPRD00774
NP_005336.23337-Heat shock 40 kDa protein 1HPRD00774
NP_005336.29530-SODDHPRD00774
NP_005336.251726-DNAJB11HPRD00774
NP_005336.210963-Stress induced phosphoprotein 1HPRD00774
NP_005336.28805-Transcriptional intermediary factor 1, alphaHPRD00774
NP_005336.25830NP_000310.2peroxisomal biogenesis factor 5HPRD02684
NP_005336.25830NP_000310.2peroxisomal biogenesis factor 5HPRD00774
NP_005336.26523NP_000334.1solute carrier family 5 (sodium/glucose cotransporter), member 1HPRD01668
NP_005336.26523NP_000334.1solute carrier family 5 (sodium/glucose cotransporter), member 1HPRD00774
NP_005336.26662NP_000337.1transcription factor SOX9HPRD06427
NP_005336.26662NP_000337.1transcription factor SOX9HPRD00774
NP_005336.25610NP_002750.1eukaryotic translation initiation factor 2-alpha kinase 2HPRD00774
NP_005336.25757NP_002814.2prothymosin, alpha (gene sequence 28)HPRD01778
NP_005336.25757NP_002814.2prothymosin, alpha (gene sequence 28)HPRD00774
NP_005336.27265NP_003305.1tetratricopeptide repeat domain 1HPRD11881
NP_005336.29131NP_004199.1programmed cell death 8 isoform 1HPRD02161
NP_005336.29131NP_004199.1programmed cell death 8 isoform 1HPRD00774
NP_005336.23855NP_005547.2keratin 7HPRD01014
NP_005336.23855NP_005547.2keratin 7HPRD00774
NP_005336.210273NP_005852.1STIP1 homology and U-Box containing protein 1HPRD06232
NP_005336.210273NP_005852.1STIP1 homology and U-Box containing protein 1HPRD00774
NP_005336.24217NP_005914.1mitogen-activated protein kinase kinase kinase 5HPRD03904
NP_005336.24217NP_005914.1mitogen-activated protein kinase kinase kinase 5HPRD00774
NP_005336.210915NP_006697.2transcription elongation regulator 1 isoform 1HPRD10393
NP_005336.210963NP_006810.1stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein)BIND183765
NP_005336.223640NP_036399.2hsp70-interacting proteinHPRD09991
NP_005336.223640NP_036399.2hsp70-interacting proteinHPRD00774
NP_005336.223645NP_055145.2protein phosphatase 1, regulatory subunit 15AHPRD06572
NP_005336.223645NP_055145.2protein phosphatase 1, regulatory subunit 15AHPRD00774
NP_005336.223118NP_055908.1mitogen-activated protein kinase kinase kinase 7 interacting protein 2HPRD05483
NP_005336.24481NP_619729.1macrophage scavenger receptor 1 isoform type 1HPRD01092
NP_005336.24481NP_619729.1macrophage scavenger receptor 1 isoform type 1HPRD00774
NP_005336.2155030NP_057850.1Pr55(Gag)--
NP_005336.2155030NP_057850.1Pr55(Gag)--
NP_005336.2155807NP_057852.2Vpr--
NP_005336.2155871NP_057853.1Tat--
NP_005336.2155030NP_579876.2matrix--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3303HSP71_HUMANP08107IPR001023Hsp70Heat shock protein Hsp70
3303HSP71_HUMANP08107IPR013126Hsp_70Heat shock protein 70

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