Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3306
Official Symbol:HSPA2
Other Aliases:-
See related:HGNC:5235|MIM:140560|HPRD:07174
Chromosome:14
Location:14q24.1
Gene Description:heat shock 70kDa protein 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0968
ORGANISM:human
Entrez Gene ID:3306
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-3 :: -1.6
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
15512CBCerebellum41.6290817260742100.0
15512CTXCerebral cortex100.0100.0
15512HIPHippocampal region100.0100.0
15512HPFHippocampal formation100.0100.0
15512HYHypothalamus89.7111282348633100.0
15512LSXLateral septal complex100.0100.0
15512MBMidbrain84.6718902587891100.0
15512MYMedulla58.481521606445387.125846862793
15512OLFOlfactory bulb100.0100.0
15512PPons55.689739227294980.845703125
15512PALPallidum96.3405532836914100.0
15512RHPRetrohippocampal region81.019424438476692.723388671875
15512sAMYStriatum-like amygdalar nuclei100.0100.0
15512STRStriatum100.0100.0
15512STRdStriatum dorsal region100.098.1013565063477
15512STRvStriatum ventral region100.0100.0
15512THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3306GO:0000166IEAFunctionnucleotide binding
3306GO:0005524IEAFunctionATP binding
3306GO:0006457IEAProcessprotein folding
3306GO:0006986TASProcessresponse to unfolded protein
3306GO:0007140TASProcessmale meiosis
3306GO:0007286TASProcessspermatid development
3306GO:0009986IEPComponentcell surface
3306GO:0051082TASFunctionunfolded protein binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_068814.223118NP_055908.1mitogen-activated protein kinase kinase kinase 7 interacting protein 2HPRD05483
NP_068814.2155030NP_057850.1Pr55(Gag)--
NP_068814.2155030NP_057850.1Pr55(Gag)--
NP_068814.2155807NP_057852.2Vpr--
NP_068814.2155871NP_057853.1Tat--
NP_068814.2155030NP_579876.2matrix--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3306HSP72_HUMANP54652IPR001023Hsp70Heat shock protein Hsp70
3306HSP72_HUMANP54652IPR013126Hsp_70Heat shock protein 70

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