Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3315
Official Symbol:HSPB1
Other Aliases:CMT2F|DKFZp586P1322|HS.76067|HSP27|HSP28|Hsp25
See related:HGNC:5246|MIM:602195|HPRD:09076
Chromosome:7
Location:7q11.23
Gene Description:heat shock 27kDa protein 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0521
ORGANISM:human
Entrez Gene ID:3315
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24471
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
15507CBCerebellum2.950203418731693.98583126068115
15507CTXCerebral cortex0.6011698842048650.758268386125565
15507HIPHippocampal region1.827199757099152.0207449644804
15507HPFHippocampal formation1.496631264686581.60639744997025
15507HYHypothalamus0.1769111454486850.246942788362503
15507LSXLateral septal complex0.03420128021389250.0
15507MBMidbrain0.1706762313842770.300879642367363
15507MYMedulla2.22209608554844.77073812484741
15507OLFOlfactory bulb0.6773200929164891.20269252359867
15507PPons0.8437761068344121.94157338142395
15507PALPallidum0.3781194165349010.694470345973969
15507RHPRetrohippocampal region0.7812855839729310.868362039327621
15507sAMYStriatum-like amygdalar nuclei0.5791675448417660.358180351555347
15507STRStriatum0.3583001121878620.326693564653397
15507STRdStriatum dorsal region0.2234743237495420.205001875758171
15507STRvStriatum ventral region0.8465373367071150.814726978540421
15507THThalamus0.1988190561532970.229456074535847
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3315GO:0005515IPIFunctionprotein binding
3315GO:0005737TASComponentcytoplasm
3315GO:0005856TASComponentcytoskeleton
3315GO:0006446TASProcessregulation of translational initiation
3315GO:0006457IEAProcessprotein folding
3315GO:0006916TASProcessanti-apoptosis
3315GO:0006928TASProcesscell motility
3315GO:0006986TASProcessresponse to unfolded protein
3315GO:0009986IEPComponentcell surface
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001531.19261--BIND195803
NP_001531.110248NP_005828.1processing of precursor 7, ribonuclease P subunitBIND199827
NP_001531.126353NP_055180.1heat shock 27kDa protein 8HPRD06420
NP_001531.126353NP_055180.1heat shock 27kDa protein 8HPRD09076
NP_001531.126353NP_055180.1heat shock 27kDa protein 8BIND134094
NP_001531.19261NP_116584.2mitogen-activated protein kinase-activated protein kinase 2 isoform 2HPRD11882
NP_001531.18550NP_620777.1mitogen-activated protein kinase-activated protein kinase 5 isoform 2HPRD09467
NP_001531.18550NP_620777.1mitogen-activated protein kinase-activated protein kinase 5 isoform 2HPRD09076
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3315HSPB1_HUMANP04792IPR001436Crystallin_alphaAlpha crystallin
3315HSPB1_HUMANP04792IPR002068Hsp20Heat shock protein Hsp20

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.