Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3326
Official Symbol:HSP90AB1
Other Aliases:D6S182|FLJ26984|HSP90-BETA|HSP90B|HSPC2|HSPCB
See related:HGNC:5258|MIM:140572|HPRD:06763
Gene Description:heat shock protein 90kDa alpha (cytosolic), class B member 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
Entrez Gene ID:3326
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.4 :: 1.5
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3326GO:0000166IEAFunctionnucleotide binding
3326GO:0005524IEAFunctionATP binding
3326GO:0006457IEAProcessprotein folding
3326GO:0006986IEAProcessresponse to unfolded protein
3326GO:0006986ISSProcessresponse to unfolded protein
3326GO:0006986NASProcessresponse to unfolded protein
3326GO:0008372NDComponentcellular component unknown
3326GO:0030235ISSFunctionnitric-oxide synthase regulator activity
3326GO:0030911ISSFunctionTPR domain binding
3326GO:0045429ISSProcesspositive regulation of nitric oxide biosynthesis
3326GO:0051082IEAFunctionunfolded protein binding
3326GO:0051082ISSFunctionunfolded protein binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_031381.28717NP_003780.1TNFRSF1A-associated via death domain isoform 1HPRD04610
NP_031381.28976NP_003932.3Wiskott-Aldrich syndrome gene-like proteinBIND295179
NP_031381.25481NP_005029.1peptidylprolyl isomerase DHPRD11875
NP_031381.26885NP_663304.1mitogen-activated protein kinase kinase kinase 7 isoform BHPRD04011
NP_031381.290627NP_821074.1START domain containing 13 isoform alphaHPRD11607
NP_031381.290627NP_821074.1START domain containing 13 isoform alphaBIND218740
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3326HS90B_HUMANP08238IPR003594ATP_bd_ATPaseATP-binding region, ATPase-like
3326HS90B_HUMANP08238IPR001404Hsp90Heat shock protein Hsp90

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