Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:347
Official Symbol:APOD
Other Aliases:-
See related:HGNC:612|MIM:107740|HPRD:00134
Chromosome:3
Location:3q26.2-qter
Gene Description:apolipoprotein D
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0190
ORGANISM:human
Entrez Gene ID:347
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15312160
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Upregulated
Fold Change:-
KARG Evidence 2
KARG ID:EVIM0289
ORGANISM:human
Entrez Gene ID:347
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Downregulated
Fold Change:-0.71
KARG Evidence 3
KARG ID:EVIM0368
ORGANISM:human
Entrez Gene ID:347
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.4 :: -1.8 :: 2.2 :: 2.1 :: 1.1 :: -1.1
KARG Evidence 4
KARG ID:EVIM0436
ORGANISM:human
Entrez Gene ID:347
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Upregulated
Fold Change:1.3 :: 1.3 :: -1.2 :: 1.8 :: 1.6
KARG Evidence 5
KARG ID:EVIM0828
ORGANISM:human
Entrez Gene ID:347
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.6 :: -1.8 :: -1.8 :: -1.4
KARG Evidence 6
KARG ID:EVIM0829
ORGANISM:human
Entrez Gene ID:347
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.5 :: -1.9
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
347GO:0005319TASFunctionlipid transporter activity
347GO:0005515IPIFunctionprotein binding
347GO:0005615TASComponentextracellular space
347GO:0006629TASProcesslipid metabolism
347GO:0006810IEAProcesstransport
347GO:0008035NRFunctionhigh-density lipoprotein binding
347GO:0008289IEAFunctionlipid binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-3953NP_002294.1leptin receptorHPRD03001
NP_001638.13953-Leptin receptorHPRD00134
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
347APOD_HUMANP05090IPR002968A1-microgloblnAlpha-1-microglobulin
347APOD_HUMANP05090IPR002969ApolipopDApolipoprotein D
347APOD_HUMANP05090IPR003057Invtbrt_colorInvertebrate colouration protein
347APOD_HUMANP05090IPR002345LipocalinLipocalin
347APOD_HUMANP05090IPR013208Lipocalin_2Lipocalin-like
347APOD_HUMANP05090IPR002446Lipocaln_bac_plnLipocalin, bacterial and plant
347APOD_HUMANP05090IPR000566Lipocln_cytFABPLipocalin-related protein and Bos/Can/Equ allergen
347APOD_HUMANP05090IPR002972PstgldnD_synthProstaglandin D synthase
347APOD_HUMANP05090IPR002449Retinol_bdRetinol-binding protein

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