Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3481
Official Symbol:IGF2
Other Aliases:FLJ44734|INSIGF
See related:HGNC:5466|MIM:147470
Chromosome:11
Location:11p15.5
Gene Description:insulin-like growth factor 2 (somatomedin A)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0558
ORGANISM:human
Entrez Gene ID:3481
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24483
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
16002CBCerebellum7.903467178344739.81308126449585
16002CTXCerebral cortex29.638869643211418.0763843655586
16002HIPHippocampal region26.366423964500421.5055366754532
16002HPFHippocampal formation25.629964232444820.2300291061401
16002HYHypothalamus25.834267497062716.3507507443428
16002LSXLateral septal complex33.07002925872818.3812683224678
16002MBMidbrain18.818157136440314.9266837835312
16002MYMedulla8.037221670150769.47958433628082
16002OLFOlfactory bulb31.268848776817321.0421336889267
16002PPons29.54757201671621.28990483284
16002PALPallidum29.094981133937818.2240960299969
16002RHPRetrohippocampal region24.55718159675618.3093090057373
16002sAMYStriatum-like amygdalar nuclei13.299401581287410.6683776378632
16002STRStriatum25.405125141143815.1417027413845
16002STRdStriatum dorsal region27.54963052272816.5980850458145
16002STRvStriatum ventral region20.230585426092110.2974562048912
16002THThalamus29.939449667930619.4792731404305
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3481GO:0000074IEAProcessregulation of progression through cell cycle
3481GO:0001501TASProcessskeletal development
3481GO:0005159TASFunctioninsulin-like growth factor receptor binding
3481GO:0005179IEAFunctionhormone activity
3481GO:0005576IEAComponentextracellular region
3481GO:0006349TASProcessimprinting
3481GO:0007275TASProcessdevelopment
3481GO:0007582IEAProcessphysiological process
3481GO:0008083IEAFunctiongrowth factor activity
3481GO:0008283IEAProcesscell proliferation
3481GO:0008286TASProcessinsulin receptor signaling pathway
3481GO:0018445IEAFunctionprothoracicotrophic hormone activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-3643NP_000199.1insulin receptorHPRD00975
-3484NP_000587.1insulin-like growth factor binding protein 1 isoform a precursorHPRD00897
-3485NP_000588.1insulin-like growth factor binding protein 2 (36kD)HPRD00898
AAA52443.13485-IGF binding protein 2HPRD00939
AAA52443.13643-Insulin receptorHPRD00939
AAA52443.13484-IGF binding protein 1HPRD00939
AAA52443.13488NP_000590.1insulin-like growth factor binding protein 5HPRD00939
AAA52443.13488NP_000590.1insulin-like growth factor binding protein 5HPRD00901
AAA52443.17448NP_000629.2vitronectin precursorHPRD00939
AAA52443.17448NP_000629.2vitronectin precursorHPRD01902
AAA52443.13487NP_001543.1insulin-like growth factor binding protein 4HPRD00939
AAA52443.13487NP_001543.1insulin-like growth factor binding protein 4HPRD00900
AAA52443.13490NP_001544.1insulin-like growth factor binding protein 7HPRD04183
AAA52443.13490NP_001544.1insulin-like growth factor binding protein 7HPRD00939
AAA52443.13489NP_002169.1insulin-like growth factor binding protein 6HPRD00939
AAA52443.13489NP_002169.1insulin-like growth factor binding protein 6HPRD00902
AAA52443.14856NP_002505.1nov precursorHPRD00939
AAA52443.14856NP_002505.1nov precursorHPRD01291
NP_000603.13484NP_000587.1insulin-like growth factor binding protein 1 isoform a precursorBIND149178
NP_000603.13485NP_000588.1insulin-like growth factor binding protein 2 (36kD)BIND149179
NP_000603.13486NP_000589.1insulin-like growth factor binding protein 3BIND149180
NP_000603.13488NP_000590.1insulin-like growth factor binding protein 5BIND146558
NP_000603.13487NP_001543.1insulin-like growth factor binding protein 4BIND149019
NP_000603.13489NP_002169.1insulin-like growth factor binding protein 6BIND146565
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3481IGF2_HUMANP01344IPR013576IGF2_CInsulin-like growth factor II E-peptide, C-terminal
3481IGF2_HUMANP01344IPR004825Ins/IGF/relaxInsulin/IGF/relaxin

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