Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:358
Official Symbol:AQP1
Other Aliases:AQP-CHIP|CHIP28|CO|MGC26324
See related:HGNC:633|MIM:107776|HPRD:00140
Chromosome:7
Location:7p14
Gene Description:aquaporin 1 (Colton blood group)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0848
ORGANISM:human
Entrez Gene ID:358
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.8 :: -2.2 :: -4.1 :: -4.5
KARG Evidence 2
KARG ID:QTL0102
ORGANISM:human
Entrez Gene ID:358
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
KARG Evidence 3
KARG ID:QTL0102
Trait:METH responses for body temperature
Peak:27
Peak Marker:D6Ncvs34
Parents:C57BL/6J x DBA/2J intercross
Evidence ID:8987796
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
358GO:0005215IEAFunctiontransporter activity
358GO:0005372TASFunctionwater transporter activity
358GO:0005887TASComponentintegral to plasma membrane
358GO:0006810IEAProcesstransport
358GO:0006833TASProcesswater transport
358GO:0007588TASProcessexcretion
358GO:0015288IEAFunctionporin activity
358GO:0016020IEAComponentmembrane
358GO:0016021IEAComponentintegral to membrane
358GO:0019867IEAComponentouter membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_000376.1358NP_000376.1aquaporin 1HPRD00140
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
358AQP1_HUMANP29972IPR002330Lipase_lipoLipoprotein lipase
358AQP1_HUMANP29972IPR000425MIPMajor intrinsic protein

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