Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3707
Official Symbol:ITPKB
Other Aliases:IP3K|IP3K-B|PIG37
See related:HGNC:6179|MIM:147522
Chromosome:1
Location:1q42.13
Gene Description:inositol 1,4,5-trisphosphate 3-kinase B
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0603
ORGANISM:human
Entrez Gene ID:3707
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:54260
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:QTL0027
ORGANISM:human
Entrez Gene ID:3707
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 3
KARG ID:QTL0028
ORGANISM:human
Entrez Gene ID:3707
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
320404CBCerebellum9.9461766481399513.5015102624893
320404CTXCerebral cortex5.709403276443485.02351397275925
320404HIPHippocampal region5.608880490064627.27488207817078
320404HPFHippocampal formation3.890445053577424.69837617874146
320404HYHypothalamus3.773087278008463.32225021719933
320404LSXLateral septal complex3.197798967361453.37708127498627
320404MBMidbrain5.923030897974975.75812277197838
320404MYMedulla11.779475271701812.5046580433846
320404OLFOlfactory bulb6.372018143534665.42094922065735
320404PPons9.3678295910358410.1362674832344
320404PALPallidum3.146652679890393.06638673320413
320404RHPRetrohippocampal region1.388420812785631.46713565289974
320404sAMYStriatum-like amygdalar nuclei1.13791702687741.22319909185171
320404STRStriatum2.534691065549852.50911600887775
320404STRdStriatum dorsal region2.094045128673322.49043004587293
320404STRvStriatum ventral region4.448457542806862.85875169187784
320404THThalamus5.85203653573995.48164451122284
KARG Evidence 4
KARG ID:QTL0027
Trait:ethanol induced locomotion
Peak:100
Peak Marker:NA
Parents:(BALB/cJ x LP/J)F2
Evidence ID:11166067
KARG Evidence 5
KARG ID:QTL0028
Trait:Chronic ethanol withdrawal
Peak:100
Peak Marker:D1Mit150
Parents:B6D2F2 (C57BL/6J x DBA/2J)
Evidence ID:11919667
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3707GO:0000166IEAFunctionnucleotide binding
3707GO:0005516IEAFunctioncalmodulin binding
3707GO:0005524IEAFunctionATP binding
3707GO:0007165TASProcesssignal transduction
3707GO:0008440TASFunctioninositol trisphosphate 3-kinase activity
3707GO:0016301IEAFunctionkinase activity
3707GO:0016740IEAFunctiontransferase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
CAC40650.1--CalmodulinHPRD00942
CAC40650.1--Protein kinase AHPRD00942
CAC40650.1--Protein kinase CHPRD00942
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3707IP3KB_HUMANP27987IPR005522IPKInositol polyphosphate kinase

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