Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3726
Official Symbol:JUNB
Other Aliases:-
See related:HGNC:6205|MIM:165161|HPRD:01303
Chromosome:19
Location:19p13.2
Gene Description:jun B proto-oncogene
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0303
ORGANISM:human
Entrez Gene ID:3726
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:16477
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIC0535
ORGANISM:human
Entrez Gene ID:3726
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24517
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
16477CBCerebellum27.55744552612330.2716541290283
16477CTXCerebral cortex28.965484619140621.5554103851318
16477HIPHippocampal region37.0637416839627.1725130081177
16477HPFHippocampal formation37.44634628295929.3789348602295
16477HYHypothalamus11.9378767013558.69061875343323
16477LSXLateral septal complex19.083525657653815.882981300354
16477MBMidbrain15.134577751159711.5191819667816
16477MYMedulla19.346950054168717.8978900909424
16477OLFOlfactory bulb52.498115539550836.7136516571045
16477PPons16.68588733673115.0521459579468
16477PALPallidum9.271127700805667.63996577262878
16477RHPRetrohippocampal region42.502807617187534.1959590911865
16477sAMYStriatum-like amygdalar nuclei18.062434196472215.9881625175476
16477STRStriatum17.876691341400113.2575511932373
16477STRdStriatum dorsal region13.3788008689889.66032600402832
16477STRvStriatum ventral region31.795861244201721.5351624488831
16477THThalamus17.239363670349111.8292427062988
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3726GO:0000785TASComponentchromatin
3726GO:0003700IEAFunctiontranscription factor activity
3726GO:0003702TASFunctionRNA polymerase II transcription factor activity
3726GO:0003713TASFunctiontranscription coactivator activity
3726GO:0003714TASFunctiontranscription corepressor activity
3726GO:0005634IEAComponentnucleus
3726GO:0006350IEAProcesstranscription
3726GO:0006357TASProcessregulation of transcription from RNA polymerase II promoter
3726GO:0043565IEAFunctionsequence-specific DNA binding
3726GO:0046983IEAFunctionprotein dimerization activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-4779NP_003195.1nuclear factor (erythroid-derived 2)-like 1HPRD01223
-4089NP_005350.1MAD, mothers against decapentaplegic homolog 4HPRD02995
-8061NP_005429.1FOS-like antigen 1HPRD00643
-122953NP_569736.1Jun dimerization proteinHPRD16360
-5599NP_620637.1mitogen-activated protein kinase 8 isoform 1HPRD03100
NP_002220.1--B-ATFHPRD01303
NP_002220.15599-JNK1HPRD01303
NP_002220.14779-Nuclear factor erythroid 2 like 1HPRD01303
NP_002220.14089-SMAD4HPRD01303
NP_002220.18061-Fos-like antigen 1HPRD01303
NP_002220.13726NP_002220.1jun B proto-oncogeneHPRD01303
NP_002220.14088NP_005893.1MAD, mothers against decapentaplegic homolog 3HPRD04380
NP_002220.14088NP_005893.1MAD, mothers against decapentaplegic homolog 3HPRD01303
NP_002220.110538NP_006390.1basic leucine zipper transcription factor, ATF-likeHPRD09820
NP_002220.110538NP_006390.1basic leucine zipper transcription factor, ATF-likeHPRD01303
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3726JUNB_HUMANP17275IPR011616bZIP_1bZIP transcription factor, bZIP_1
3726JUNB_HUMANP17275IPR011700bZIP_2Basic leucine zipper
3726JUNB_HUMANP17275IPR002952EggshellEggshell protein
3726JUNB_HUMANP17275IPR005643JNKJun-like transcription factor
3726JUNB_HUMANP17275IPR002112Leuzip_JunTranscription factor Jun
3726JUNB_HUMANP17275IPR000817PrionPrion protein
3726JUNB_HUMANP17275IPR004827TF_bZIPBasic-leucine zipper (bZIP) transcription factor

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