Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3746
Official Symbol:KCNC1
Other Aliases:KV3.1|KV4|MGC129855|NGK2
See related:HGNC:6233|MIM:176258|HPRD:15936
Chromosome:11
Location:11p15
Gene Description:potassium voltage-gated channel, Shaw-related subfamily, member 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0047
ORGANISM:human
Entrez Gene ID:3746
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:16502
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
16502CBCerebellum100.0100.0
16502CTXCerebral cortex69.54086494445878.9315490722656
16502HIPHippocampal region65.082286834716891.1225128173828
16502HPFHippocampal formation60.535776138305785.2317504882812
16502HYHypothalamus58.559259414672964.6506366729736
16502LSXLateral septal complex13.49179267883311.7665019035339
16502MBMidbrain93.6332321166992100.0
16502MYMedulla85.3236274719238100.0
16502OLFOlfactory bulb67.268989562988384.0443267822266
16502PPons79.4912986755371100.0
16502PALPallidum61.846315383911187.867130279541
16502RHPRetrohippocampal region56.201295852661166.6807518005371
16502sAMYStriatum-like amygdalar nuclei52.329149246215849.4055252075195
16502STRStriatum20.775007247924821.7653102874756
16502STRdStriatum dorsal region15.428390979766817.1844329833984
16502STRvStriatum ventral region24.257736206054724.5760927200317
16502THThalamus96.1480522155762100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3746GO:0005249TASFunctionvoltage-gated potassium channel activity
3746GO:0005515IEAFunctionprotein binding
3746GO:0005624NRComponentmembrane fraction
3746GO:0006812IEAProcesscation transport
3746GO:0006813TASProcesspotassium ion transport
3746GO:0008076TASComponentvoltage-gated potassium channel complex
3746GO:0016020IEAComponentmembrane
3746GO:0016021IEAComponentintegral to membrane
3746GO:0030955IEAFunctionpotassium ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_004967.1170850NP_579875.1potassium voltage-gated channel, subfamily G, member 3 isoform 1HPRD16232
NP_004967.1170850NP_579875.1potassium voltage-gated channel, subfamily G, member 3 isoform 1HPRD15936
NP_004967.1169522NP_598004.1potassium channel, subfamily V, member 2HPRD15936
NP_004967.1169522NP_598004.1potassium channel, subfamily V, member 2HPRD12126
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3746KCNC1_HUMANP48547IPR005821Ion_transIon transport
3746KCNC1_HUMANP48547IPR013099Ion_trans_2_bacIon transport 2, bacterial
3746KCNC1_HUMANP48547IPR013621Ion_trans_NIon transport N-terminal
3746KCNC1_HUMANP48547IPR001622K+channel_poreK+ channel, pore region
3746KCNC1_HUMANP48547IPR005403KV3.1_channelKv3.1 voltage-gated K+ channel
3746KCNC1_HUMANP48547IPR003969Kv6_channelKv6 voltage-gated K+ channel
3746KCNC1_HUMANP48547IPR003971Kv9_channelKv9 voltage-gated K+ channel
3746KCNC1_HUMANP48547IPR003968Kv_channelKv channel
3746KCNC1_HUMANP48547IPR003091K_channelVoltage-dependent potassium channel
3746KCNC1_HUMANP48547IPR003131K_tetraK+ channel tetramerisation
3746KCNC1_HUMANP48547IPR005820M+channel_nlgCation channel, non-ligand gated
3746KCNC1_HUMANP48547IPR003974Shaw_channelShaw voltage-gated K+ channel

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.