Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3766
Official Symbol:KCNJ10
Other Aliases:BIRK-10|KCNJ13-PEN|KIR1.2|KIR4.1
See related:HGNC:6256|MIM:602208|HPRD:03732
Chromosome:1
Location:1q22-q23
Gene Description:potassium inwardly-rectifying channel, subfamily J, member 10
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0398
ORGANISM:human
Entrez Gene ID:3766
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:29718
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIM0849
ORGANISM:human
Entrez Gene ID:3766
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.5 :: -1.9
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3766GO:0000166IEAFunctionnucleotide binding
3766GO:0005244IEAFunctionvoltage-gated ion channel activity
3766GO:0005267IEAFunctionpotassium channel activity
3766GO:0005524IEAFunctionATP binding
3766GO:0005887TASComponentintegral to plasma membrane
3766GO:0006811IEAProcession transport
3766GO:0006813TASProcesspotassium ion transport
3766GO:0015272TASFunctionATP-activated inward rectifier potassium channel activity
3766GO:0016020IEAComponentmembrane
3766GO:0030955IEAFunctionpotassium ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-3773NP_061128.1potassium inwardly-rectifying channel J16HPRD16146
-10207NP_733750.2InaD-like protein isoform 1HPRD04434
NP_002232.2--Kir5.1HPRD03732
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3766IRK10_HUMANP78508IPR013673IRK_NInward rectifier potassium channel N-terminal
3766IRK10_HUMANP78508IPR001622K+channel_poreK+ channel, pore region
3766IRK10_HUMANP78508IPR013521K+channel_IR_Cr2K+ channel, inward rectifier, conserved region 2
3766IRK10_HUMANP78508IPR003268KIR11_channelKir1.1 inward rectifier K+ channel
3766IRK10_HUMANP78508IPR003269KIR12_channelKir1.2 inward rectifier K+ channel
3766IRK10_HUMANP78508IPR008062KIR7_channelKir7 inward rectifier K+ channel

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.