Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:377
Official Symbol:ARF3
Other Aliases:-
See related:HGNC:654|MIM:103190|HPRD:00056
Chromosome:12
Location:12q13
Gene Description:ADP-ribosylation factor 3
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0966
ORGANISM:human
Entrez Gene ID:377
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated/Downregulated
Fold Change:1.2 :: 1.1 :: -1.5 :: -1.4
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
11842CBCerebellum30.135420004526845.9834324518839
11842CTXCerebral cortex92.011334737141989.8965352376302
11842HIPHippocampal region100.0100.0
11842HPFHippocampal formation98.6251271565755100.0
11842HYHypothalamus52.046917279561448.9159681002299
11842LSXLateral septal complex74.670173645019572.6049671173096
11842MBMidbrain50.742754618326850.4935499827067
11842MYMedulla50.298164685567253.7252330780029
11842OLFOlfactory bulb96.318181355794388.3127772013346
11842PPons45.824823220570951.0965328216553
11842PALPallidum60.338834444681859.9970184961955
11842RHPRetrohippocampal region83.448061625162880.4325637817383
11842sAMYStriatum-like amygdalar nuclei96.87706756591887.2883288065592
11842STRStriatum99.833808898925890.9290084838867
11842STRdStriatum dorsal region100.093.3514506022135
11842STRvStriatum ventral region100.090.9161631266276
11842THThalamus46.07310398419745.6908916632334
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
377GO:0000166IEAFunctionnucleotide binding
377GO:0005525IEAFunctionGTP binding
377GO:0005622IEAComponentintracellular
377GO:0005795IEAComponentGolgi stack
377GO:0006364IEAProcessrRNA processing
377GO:0006888IEAProcessER to Golgi vesicle-mediated transport
377GO:0007264IEAProcesssmall GTPase mediated signal transduction
377GO:0015031IEAProcessprotein transport
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001650.1--Arfaptin 1HPRD00056
NP_001650.126088--BIND199782
NP_001650.123647NP_036534.1ADP-ribosylation factor interacting protein 2 (arfaptin 2)HPRD07209
NP_001650.123647NP_036534.1ADP-ribosylation factor interacting protein 2 (arfaptin 2)HPRD00056
NP_001650.127236NP_055262.1ADP-ribosylation factor interacting protein 1 isoform 2HPRD09331
NP_001650.127236NP_055262.1ADP-ribosylation factor interacting protein 1 isoform 2HPRD00056
NP_001650.123062NP_055859.1ADP-ribosylation factor binding protein 2HPRD09347
NP_001650.19493NP_612565.1kinesin family member 23 isoform 1HPRD05455
NP_001650.19493NP_612565.1kinesin family member 23 isoform 1HPRD00056
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
377ARF3_HUMANP61204IPR006688ARFADP-ribosylation factor
377ARF3_HUMANP61204IPR006689ARF/SARARF/SAR superfamily
377ARF3_HUMANP61204IPR013753RasRas
377ARF3_HUMANP61204IPR001806Ras_trnsfrmngRas GTPase

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