Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:379
Official Symbol:ARL4D
Other Aliases:ARF4L|ARL6
See related:HGNC:656|MIM:600732|HPRD:02842
Chromosome:17
Location:17q12-q21
Gene Description:ADP-ribosylation factor-like 4D
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0184
ORGANISM:human
Entrez Gene ID:379
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15312160
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:-
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
66182CBCerebellum11.657475948333713.5004253387451
66182CTXCerebral cortex65.173133850097754.7495746612549
66182HIPHippocampal region17.306466102600119.672191619873
66182HPFHippocampal formation22.832272529602122.906512260437
66182HYHypothalamus7.522233009338386.16507577896118
66182LSXLateral septal complex17.236876010894820.1581411361694
66182MBMidbrain11.05692911148079.48608064651489
66182MYMedulla28.927102088928230.6980714797974
66182OLFOlfactory bulb57.56267166137756.7631988525391
66182PPons15.002040386215.078013420105
66182PALPallidum20.183317184448220.5142822265625
66182RHPRetrohippocampal region30.309464454650925.8928327560425
66182sAMYStriatum-like amygdalar nuclei17.064943313598614.8694987297058
66182STRStriatum65.343784332275458.3481006622314
66182STRdStriatum dorsal region81.332283020019572.9721374511719
66182STRvStriatum ventral region57.166063308715848.8198146820068
66182THThalamus11.7541413307199.89964127540588
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
379GO:0000166IEAFunctionnucleotide binding
379GO:0003924TASFunctionGTPase activity
379GO:0005525IEAFunctionGTP binding
379GO:0005634IEAComponentnucleus
379GO:0006364IEAProcessrRNA processing
379GO:0007264IEAProcesssmall GTPase mediated signal transduction
379GO:0009306TASProcessprotein secretion
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001652.123204NP_055976.1ADP-ribosylation factor-like 6 interacting proteinHPRD02842
NP_001652.123204NP_055976.1ADP-ribosylation factor-like 6 interacting proteinHPRD09641
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
379ARL4D_HUMANP49703IPR006689ARF/SARARF/SAR superfamily
379ARL4D_HUMANP49703IPR006073GTP1_OBGGTP1/OBG
379ARL4D_HUMANP49703IPR013684Miro-likeMiro-like
379ARL4D_HUMANP49703IPR013753RasRas
379ARL4D_HUMANP49703IPR001806Ras_trnsfrmngRas GTPase

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