Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3916
Official Symbol:LAMP1
Other Aliases:CD107a|LAMPA|LGP120
See related:HGNC:6499|MIM:153330|HPRD:01076
Chromosome:13
Location:13q34
Gene Description:lysosomal-associated membrane protein 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0266
ORGANISM:human
Entrez Gene ID:3916
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Downregulated
Fold Change:-0.67
KARG Evidence 2
KARG ID:EVIM0944
ORGANISM:human
Entrez Gene ID:3916
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.6 :: -1.5
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
16783CBCerebellum99.4616546630859100.0
16783CTXCerebral cortex100.0100.0
16783HIPHippocampal region92.669563293457100.0
16783HPFHippocampal formation100.0100.0
16783HYHypothalamus100.0100.0
16783LSXLateral septal complex100.0100.0
16783MBMidbrain100.0100.0
16783MYMedulla100.0100.0
16783OLFOlfactory bulb100.0100.0
16783PPons100.0100.0
16783PALPallidum100.0100.0
16783RHPRetrohippocampal region100.0100.0
16783sAMYStriatum-like amygdalar nuclei100.0100.0
16783STRStriatum99.011085510253997.581916809082
16783STRdStriatum dorsal region96.360641479492297.8095321655273
16783STRvStriatum ventral region78.679534912109469.3586349487305
16783THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3916GO:0005624TASComponentmembrane fraction
3916GO:0005764IDAComponentlysosome
3916GO:0005770IDAComponentlate endosome
3916GO:0005887TASComponentintegral to plasma membrane
3916GO:0016020IEAComponentmembrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-8907NP_115882.1adaptor-related protein complex 1, mu 1 subunitHPRD04639
NP_005552.2--AP-3HPRD01076
NP_005552.28907-AP47HPRD01076
NP_005552.2155030NP_579880.1capsid--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3916LAMP1_HUMANP11279IPR003980H3_rcptHistamine H3 receptor
3916LAMP1_HUMANP11279IPR002000LampLysosome-associated membrane glycoprotein (Lamp)/CD68
3916LAMP1_HUMANP11279IPR000694PRO_richProline-rich region

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