Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3920
Official Symbol:LAMP2
Other Aliases:CD107b|LAMP-2C|LAMPB
See related:HGNC:6501|MIM:309060|HPRD:02396
Chromosome:X
Location:Xq24
Gene Description:lysosomal-associated membrane protein 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0352
ORGANISM:human
Entrez Gene ID:3920
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:-0.79
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
16784CBCerebellum0.00.0
16784CTXCerebral cortex0.00.0
16784HIPHippocampal region0.00.0
16784HPFHippocampal formation0.00.0
16784HYHypothalamus0.00.0
16784LSXLateral septal complex0.00.0
16784MBMidbrain0.00.0
16784MYMedulla0.00.0
16784OLFOlfactory bulb0.00.0
16784PPons0.00.0
16784PALPallidum0.00.0
16784RHPRetrohippocampal region0.00.0
16784sAMYStriatum-like amygdalar nuclei0.00.0
16784STRStriatum0.00.0
16784STRdStriatum dorsal region0.00.0
16784STRvStriatum ventral region0.00.0
16784THThalamus0.00.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3920GO:0005624IDAComponentmembrane fraction
3920GO:0005765IDAComponentlysosomal membrane
3920GO:0016020IEAComponentmembrane
3920GO:0016021IEAComponentintegral to membrane
3920GO:0031088IDAComponentplatelet dense granule membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_002285.16622NP_000336.1alpha-synuclein isoform NACP140BIND151734
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3920IPR002000LampLysosome-associated membrane glycoprotein (Lamp)/CD68
3920LAMP2_HUMANP13473IPR002000LampLysosome-associated membrane glycoprotein (Lamp)/CD68

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