Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3921
Official Symbol:RPSA
Other Aliases:37LRP|67LR|LAMBR|LAMR1|LRP|p40
See related:HGNC:6502|MIM:150370|HPRD:01038
Chromosome:3
Location:3p22.2
Gene Description:ribosomal protein SA
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0120
ORGANISM:human
Entrez Gene ID:3921
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12629581
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Dorsolateral Prefrontal Cortex
Drug Effects:Upregulated/Downregulated
Fold Change:1.61 :: 0.63 :: 0.78 :: 0.32 :: -1.20 :: -1.65 :: -2.65
KARG Evidence 2
KARG ID:QTL0157
ORGANISM:human
Entrez Gene ID:3921
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 3
KARG ID:QTL0158
ORGANISM:human
Entrez Gene ID:3921
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 4
KARG ID:QTL0159
ORGANISM:human
Entrez Gene ID:3921
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
KARG Evidence 5
KARG ID:QTL0157
Trait:METH responses for body temperature
Peak:71
Peak Marker:Cck
Parents:C57BL/6J x DBA/2J intercross
Evidence ID:8987796
KARG Evidence 6
KARG ID:QTL0158
Trait:METH responses for body temperature
Peak:71
Peak Marker:D9Byu6
Parents:C57BL/6J x DBA/2J intercross
Evidence ID:8987796
KARG Evidence 7
KARG ID:QTL0159
Trait:ethanol withdrawal
Peak:71
Peak Marker:D9Byu6
Parents:C57BL/6J x DBA/2J intercross
Evidence ID:9655868
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3921GO:0003735IEAFunctionstructural constituent of ribosome
3921GO:0005055TASFunctionlaminin receptor activity
3921GO:0005634TASComponentnucleus
3921GO:0005843NRComponentcytosolic small ribosomal subunit (sensu Eukaryota)
3921GO:0006412IEAProcessprotein biosynthesis
3921GO:0006445NRProcessregulation of translation
3921GO:0007155NASProcesscell adhesion
3921GO:0007166NRProcesscell surface receptor linked signal transduction
3921GO:0008305NRComponentintegrin complex
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-23468NP_036249.1chromobox homolog 5 (HP1 alpha homolog, Drosophila)HPRD05131
NP_002286.2--Laminin-1HPRD01038
NP_002286.223468-HP1 alphaHPRD01038
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3921RSSA_HUMANP08865IPR001865Ribosomal_S2Ribosomal protein S2

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