Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3939
Official Symbol:LDHA
Other Aliases:LDH-M|LDH1|PIG19
See related:HGNC:6535|MIM:150000|HPRD:01025
Chromosome:11
Location:11p15.4
Gene Description:lactate dehydrogenase A
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0477
ORGANISM:human
Entrez Gene ID:3939
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24533
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
16828CBCerebellum100.0100.0
16828CTXCerebral cortex100.0100.0
16828HIPHippocampal region100.0100.0
16828HPFHippocampal formation100.0100.0
16828HYHypothalamus100.0100.0
16828LSXLateral septal complex100.0100.0
16828MBMidbrain100.0100.0
16828MYMedulla74.166877746582100.0
16828OLFOlfactory bulb100.0100.0
16828PPons74.7522354125977100.0
16828PALPallidum100.0100.0
16828RHPRetrohippocampal region100.0100.0
16828sAMYStriatum-like amygdalar nuclei100.0100.0
16828STRStriatum100.0100.0
16828STRdStriatum dorsal region100.0100.0
16828STRvStriatum ventral region100.0100.0
16828THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3939GO:0004459TASFunctionL-lactate dehydrogenase activity
3939GO:0005515IPIFunctionprotein binding
3939GO:0005829TASComponentcytosol
3939GO:0006100IEAProcesstricarboxylic acid cycle intermediate metabolism
3939GO:0016491IEAFunctionoxidoreductase activity
3939GO:0019642IEAProcessanaerobic glycolysis
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-8655NP_003737.1dynein light chain 1HPRD03334
-10060NP_005682.1ATP-binding cassette, sub-family C, member 9 isoform SUR2AHPRD03258
NP_005557.1--Kir6HPRD01025
NP_005557.1--XRN1HPRD01025
NP_005557.110060-ATP binding cassette, subfamily C, member 9HPRD01025
NP_005557.18655-DLC1HPRD01025
NP_005557.13939NP_005557.1lactate dehydrogenase AHPRD01025
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3939LDHA_HUMANP00338IPR001236lact_mal_DHLactate/malate dehydrogenase
3939LDHA_HUMANP00338IPR001557L_LDH_MDHL-lactate/malate dehydrogenase
3939LDHA_HUMANP00338IPR011304L_LDH_NADL-lactate dehydrogenase
3939LDHA_HUMANP00338IPR001806Ras_trnsfrmngRas GTPase

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