Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3945
Official Symbol:LDHB
Other Aliases:LDH-H|TRG-5
See related:HGNC:6541|MIM:150100|HPRD:01026
Chromosome:12
Location:12p12.2-p12.1
Gene Description:lactate dehydrogenase B
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0390
ORGANISM:human
Entrez Gene ID:3945
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24534
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
433229CBCerebellum100.0100.0
433229CTXCerebral cortex100.0100.0
433229HIPHippocampal region94.6493988037109100.0
433229HPFHippocampal formation100.0100.0
433229HYHypothalamus100.0100.0
433229LSXLateral septal complex100.0100.0
433229MBMidbrain100.0100.0
433229MYMedulla100.0100.0
433229OLFOlfactory bulb100.0100.0
433229PPons100.0100.0
433229PALPallidum100.0100.0
433229RHPRetrohippocampal region100.0100.0
433229sAMYStriatum-like amygdalar nuclei100.0100.0
433229STRStriatum100.0100.0
433229STRdStriatum dorsal region100.0100.0
433229STRvStriatum ventral region100.0100.0
433229THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3945GO:0004459TASFunctionL-lactate dehydrogenase activity
3945GO:0005737TASComponentcytoplasm
3945GO:0006100IEAProcesstricarboxylic acid cycle intermediate metabolism
3945GO:0016491IEAFunctionoxidoreductase activity
3945GO:0019642IEAProcessanaerobic glycolysis
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_002291.13945NP_002291.1lactate dehydrogenase BHPRD01026
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3945LDHB_HUMANP07195IPR001236lact_mal_DHLactate/malate dehydrogenase
3945LDHB_HUMANP07195IPR001557L_LDH_MDHL-lactate/malate dehydrogenase
3945LDHB_HUMANP07195IPR011304L_LDH_NADL-lactate dehydrogenase

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