Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:396
Official Symbol:ARHGDIA
Other Aliases:GDIA1|MGC117248|RHOGDI
See related:HGNC:678|MIM:601925|HPRD:03565
Chromosome:17
Location:17q25.3
Gene Description:Rho GDP dissociation inhibitor (GDI) alpha
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0428
ORGANISM:human
Entrez Gene ID:396
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:360678
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
192662CBCerebellum40.379781723022551.1791906356812
192662CTXCerebral cortex97.97058868408298.4321823120117
192662HIPHippocampal region80.1513919830322100.0
192662HPFHippocampal formation87.6192359924316100.0
192662HYHypothalamus90.215282440185594.3893241882324
192662LSXLateral septal complex64.948303222656263.1108770370483
192662MBMidbrain64.440540313720765.8636922836304
192662MYMedulla71.999746322631879.5935096740723
192662OLFOlfactory bulb100.0100.0
192662PPons68.971818923950273.9706916809082
192662PALPallidum74.086320877075278.2788410186768
192662RHPRetrohippocampal region100.0100.0
192662sAMYStriatum-like amygdalar nuclei100.0100.0
192662STRStriatum84.376758575439581.0104141235352
192662STRdStriatum dorsal region81.676088333129978.6591720581055
192662STRvStriatum ventral region88.828907012939581.6139698028564
192662THThalamus68.572610855102569.2400913238525
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
396GO:0005094TASFunctionRho GDP-dissociation inhibitor activity
396GO:0005096IEAFunctionGTPase activator activity
396GO:0005515TASFunctionprotein binding
396GO:0005737IEAComponentcytoplasm
396GO:0005856TASComponentcytoskeleton
396GO:0006916TASProcessanti-apoptosis
396GO:0006928TASProcesscell motility
396GO:0007162TASProcessnegative regulation of cell adhesion
396GO:0007266TASProcessRho protein signal transduction
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-5962NP_002897.1radixinHPRD01534
-5879NP_061485.1ras-related C3 botulinum toxin substrate 1 isoform Rac1bHPRD03627
NP_004300.15962-RadixinHPRD03565
NP_004300.15879-Ras related C3 botulinum toxin substrate 1HPRD03565
NP_004300.1998NP_001782.1cell division cycle 42 isoform 1HPRD00309
NP_004300.15058NP_002567.3p21-activated kinase 1BIND149063
NP_004300.15880NP_002863.1ras-related C3 botulinum toxin substrate 2HPRD03565
NP_004300.15879NP_061485.1ras-related C3 botulinum toxin substrate 1 isoform Rac1bHPRD03627
NP_004300.1155807NP_057852.2Vpr--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
396GDIR_HUMANP52565IPR000406Rho_GDIRHO protein GDP dissociation inhibitor

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